Terbisol 1% (Cream)
10 gm tube: ৳ 80.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Terbinafine hydrochloride |
| Company | Nipro jmi pharma ltd |
Indications
- Treatment of onychomycosis of toenail or fingernail
- Treatment of Tinea Capitis
- Fungal infection of the skin
- Tinea infections of the skin
- Pityriasis versicolor
- Yeast infections of the skin
Pharmacology
- Inhibits biosynthesis of Ergosterol
- Fungicidal against Tricophyton Mentagrophyte, Trichophyton Rubrum
Dosage & Administration
- Terbinafine tablet:
- Treatment for fingernail and toenail onychomycosis
- Terbinafine granules:
- Dosage based on body weight
- Terbinafine cream:
- Duration of treatment for different skin infections
- Terbinafine 1% Spray:
- Application frequency for different conditions
Interaction
- Inhibitor of CYP450 2D6 isozyme
- May require dose reduction of 2D6-metabolized drugs
Contraindications
- Hypersensitivity to terbinafine
Side Effects
- Gastrointestinal symptoms
- Liver test abnormalities
- Rashes
- Pruritus
- Taste disturbances
- Idiosyncratic hepatic injury
- Serious skin reactions
- Neutropenia
- Thrombocytopenia
- Angioedema
- Allergic reactions
Pregnancy & Lactation
- Terbinafine tablet:
- Not recommended during pregnancy
- Not recommended in nursing mothers
- Terbinafine cream:
- Not administered in pregnant or breastfeeding women
Precautions & Warnings
- Warnings:
- Rare cases of liver failure
- Contact with eyes should be avoided
- Precautions:
- Not recommended for patients with chronic or active liver disease
- Assessment of pre-existing liver disease before prescribing
Use in Special Populations
- Pediatric use:
- Safety and efficacy not established in pediatric patients
- Use in the elderly:
- No evidence of different dosages or side-effects
Overdose Effects
- Limited clinical experience
- No serious adverse reactions reported at high doses
Therapeutic Class
- Other Antifungal preparations
- Topical Antifungal preparations
Storage Conditions
- Store below 30°C
- Protect from light