Oxalid 600 mg (Tablet)

Unit Price: ৳ 70.00 (1 x 10: ৳ 700.00)
Strip Price: ৳ 700.00

Medicine Details

Category Details
Generic Linezolid
Company General pharmaceuticals ltd
Also available as

Indications

  • Nosocomial pneumonia
  • Community-acquired pneumonia
  • Complicated skin and skin structure infection
  • Uncomplicated skin and skin structure infections
  • Vancomycin-resistant Enterococcus faecium infections

Pharmacology

Synthetic antibacterial agent, selective inhibition of bacterial protein synthesis, bacteriostatic and bactericidal activity

Dosage & Administration

  • Infection:
    • Nosocomial pneumonia
    • Community-acquired pneumonia
    • Complicated skin and skin structure infections
    • Uncomplicated skin and skin structure infections
  • Dosage, route and frequency of administration:
    • Pediatric patients: 10 mg/kg orally or intravenously every 8 hours
    • Adults and adolescent: 600 mg orally or intravenously every 12 hours
    • Recommended duration of treatment (consecutive days): 10 to 14
  • Intravenous administration: Administered by intravenous infusion over a period of 30 to 120 minutes
  • Hepatic impairment: No dose adjustment for patients with mild-to-moderate hepatic impairment

Interaction

  • Drug interaction with medication: Reversible, nonselective inhibitor of monoamine oxidase, potential interaction with adrenergic and serotonergic agents
  • Drug interaction with food and others: Avoid large quantities of foods or beverages with high tyramine content

Contraindications

  • Hypersensitivity to Linezolid or any of the other product components
  • Concurrent use with monoamine oxidase inhibitors or within two weeks of using such medication

Side Effects

  • Diarrhea
  • Headache
  • Nausea
  • Oral moniliasis
  • Vaginal moniliasis
  • Hypertension
  • Dyspepsia
  • Localized abdominal pain
  • Pruritus
  • Tongue discoloration

Pregnancy & Lactation

  • Pregnancy: Use during pregnancy only if the potential benefit justifies the potential risk to the fetus
  • Lactation: Consider developmental and health benefits of breastfeeding, monitor infant for diarrhea and vomiting if breastfeeding

Precautions & Warnings

  • Monitor complete blood counts
  • Prompt ophthalmic evaluation for visual impairment
  • Not approved for catheter-related infections
  • Monitor for potential increases in blood pressure
  • Immediate medical evaluation for certain symptoms

Overdose Effects

No cases of overdose reported, symptomatic and supportive care advised

Therapeutic Class

Macrolides

Reconstitution

  • Oral Suspension: Reconstitute with boiled and cooled water, shake well, store in a cool and dry place
  • Intravenous Administration: Administered by intravenous infusion over a period of 30 to 120 minutes

Storage Conditions

Store at room temperature (15°C-30°C), away from light and moisture, keep away from children

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