Prazover 40 mg (Capsule (Enteric Coated))

Unit Price: ৳ 8.03 (7 x 4: ৳ 224.84)
Strip Price: ৳ 32.12

Medicine Details

Indications

  • Gastric and duodenal ulcer
  • NSAID-associated duodenal and gastric ulcer
  • Gastro-esophageal reflux disease
  • Acid-related dyspepsia
  • Long-term management of acid reflux disease
  • Severe ulcerating reflux esophagitis
  • Prophylaxis of acid aspiration during general anesthesia
  • Zollinger-Ellison syndrome
  • Helicobacter pylori-induced peptic ulcer

Pharmacology

  • Inhibitor of gastric acid secretion
  • Blocks H+/K+ ATPase enzyme system
  • Onset of effect within one hour
  • Maximum effect within two hours
  • Inhibition of secretion lasts up to 72 hours

Dosage

  • Varied dosage for different conditions
  • Different dosing for oral and IV administration
  • Maintenance doses for long-term management

Administration

  • Direction for use of IV Injection
  • Direction for use of IV Infusion
  • Instructions for reconstitution and administration

Interaction

  • Possible drug interactions with ketoconazole
  • Metabolism through cytochrome P450
  • Monitoring recommended for patients on warfarin or phenytoin
  • Plasma concentration increase during co-administration
  • No evidence of interaction with certain drugs

Contraindications

  • Known hypersensitivity to omeprazole
  • Exclusion of malignancy before treatment

Side Effects

  • Skin reactions such as rash, urticaria, pruritus
  • Photosensitivity, bullous eruption, alopecia
  • Gastrointestinal reactions like diarrhea and headache
  • Neurological effects like paraesthesia, dizziness
  • Mental effects in severely ill patients
  • Musculoskeletal symptoms and hematologic reactions
  • Liver enzyme increases observed

Pregnancy & Lactation

  • No adverse effects on pregnancy or fetus/newborn child
  • Safe for use during pregnancy
  • No information on passage into breast milk
  • Discontinuation of breastfeeding if essential

Precautions & Warnings

  • Avoid concomitant use with clopidogrel
  • Potential association with increased risk for fractures
  • Atrophic gastritis in long-term use
  • Potential for methotrexate toxicities

Therapeutic Class

  • Proton Pump Inhibitor

Storage Conditions

  • Store in dry place away from light and heat

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