D-High 40000 IU (Capsule)

Unit Price: ৳ 35.00 (2 x 4: ৳ 280.00)
Strip Price: ৳ 140.00

Medicine Details

Category Details
Generic Cholecalciferol vitamin d3
Company Somatec pharmaceuticals ltd
Also available as
D high 20000 iu capsule

Indications

  • Prevention of rickets
  • Prevention of osteomalacia
  • Prevention of osteoporosis
  • Immunity boosting
  • Prevention of pre-eclampsia during pregnancy
  • Prevention of Vitamin D3 deficiency
  • Effective calcium absorption
  • Phosphate absorption for healthy bones and teeth

Pharmacology

  • Active form: Calcitriol
  • Binding to Vitamin D receptors
  • Absorbed in the small intestine
  • Metabolized to 25-hydroxy Vitamin D3
  • Metabolized to 1,25-dihydroxy Vitamin D3
  • Half-life of about 50 days
  • Fat-soluble
  • Transported to the liver
  • Stored in tissues such as fat and muscle
  • Eliminated via feces and urine

Dosage & Administration

  • Dosage for adults
  • Dosage for children
  • Dosage for specific therapy for osteoporosis
  • Dosage for different dosage forms (capsule, tablet, syrup, injection)
  • Dosage adjustments based on age and condition
  • Administration instructions (with food or after a meal)

Interaction

  • Drugs causing Vitamin D3 deficiencies
  • Drugs interfering with absorption and metabolism
  • Examples of interacting drugs (Magnesium containing Antacids, Digoxin, Thiazide Diuretics, Cholestyramine, Cholistipol, Phenytoin, Phenobarbital, Orlistat, Mineral Oil, Corticosteroids)

Contraindications

  • Hypercalcaemia
  • Hypersensitivity to Vitamin D3 or its class of medicines
  • Evidence of Vitamin D3 toxicity

Side Effects

  • Anorexia
  • Lassitude
  • Nausea & vomiting
  • Diarrhea
  • Constipation
  • Weight loss
  • Polyuria
  • Sweating
  • Headache
  • Thirst
  • Vertigo
  • Raised concentrations of calcium and phosphate in plasma and urine

Pregnancy & Lactation

  • Safe use during pregnancy
  • Excretion in breast milk
  • Potential overdose in infants induced by nursing mothers
  • Recommended daily intake for pregnant women

Precautions & Warnings

  • Plasma-calcium concentration monitoring
  • Consultation before supplementing with Vitamin D3 in specific medical conditions (renal impairment, liver or kidney disease, hyperthyroidism, lymphoma, tuberculosis, granulomatous disease)
  • Consultation for people using Digoxin and Thiazide Diuretics

Use in Special Populations

  • Safety & efficacy in children under 12 years

Overdose Effects

  • Hypervitaminosis D

Therapeutic Class

  • Vitamin in bone formation
  • Vitamin-D preparations

Storage Conditions

  • Temperature below 30°C
  • Protected from light & moisture
  • Keep out of the reach of children

Related Brands