Ondamax 4 mg (Tablet)
Unit Price: ৳ 5.00 (3 x 10: ৳ 150.00)
Strip Price: ৳ 50.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Ondansetron |
| Company | Somatec pharmaceuticals ltd |
| Also available as |
Therapeutic Class
- Anti-emetic drugs
Indications
- Prevention of nausea and vomiting associated with initial and repeat courses of emetogenic cancer chemotherapy
- Prevention and treatment of post-operative nausea and vomiting
- Prevention of radiotherapy-induced nausea and vomiting
Description
- Oral soluble film designed to be applied on top of the tongue where it will dissolve within 20 seconds
- Active ingredient: Ondansetron base
- Empirical formula: C18H19N3O
Pharmacology
- Potent, highly selective 5HT3 receptor-antagonist
- Mode of action not fully known
- Blocks 5HT3 receptors on neurons in peripheral and central nervous system
Dosage
- Different dosages for adults, pediatric patients, and radiotherapy
- Various dosage forms: tablet, orodispersible tablet, injection, oral solution
- Specific dosages for highly emetogenic and moderately emetogenic cancer chemotherapy
- Instructions for pediatric patients
Administration
- Oral Soluble Film administration steps
- Dissolves within 20 seconds on top of the tongue
Interaction
- Not a significant inducer or inhibitor of cytochrome P-450 drug-metabolizing enzymes
Contraindications
- Hypersensitivity to the drug or any of its components
- Concomitant use of apomorphine
Side Effects
- Frequent adverse events: headache, constipation, diarrhea
- Rare reports of serious side effects like anaphylaxis, bronchospasm, tachycardia
Pregnancy & Lactation
- No evidence of harm to fetus in animal studies
- Excreted in breast milk of rats
Precautions & Warnings
- Reported hypersensitivity reactions in some patients
- Should not be used instead of nasogastric suction
- May mask a progressive ileus and/or gastric distension
Use in Special Populations
- Dosage recommendations for patients with impaired renal function and hepatic function
- Limited information on dosage for pediatric patients 4 years of age or younger
Storage Conditions
- Store at temperature not exceeding 30°C in a dry place
- Protect from light and moisture