Gepril 5 mg (Tablet)

Unit Price: ৳ 8.00 (3 x 10: ৳ 240.00)
Strip Price: ৳ 80.00

Medicine Details

Category Details
Generic Ramipril
Company Globe pharmaceuticals ltd

Indications

  • Hypertension
  • Congestive heart failure
  • Acute myocardial infarction
  • Glomerular nephropathy
  • Cardiovascular risk reduction

Pharmacology

  • ACE inhibitor
  • Vasopressor activity reduction
  • Aldosterone secretion decrease
  • Antihypertensive
  • Heart failure management
  • Stroke risk reduction
  • Long-acting

Dosage

  • Initial dose adjustment
  • Dosage intervals
  • Maintenance dosage
  • Renal impairment dosage
  • Heart failure post-myocardial infarction dosage
  • Cardiovascular events prevention dosage

Administration

  • Swallowing with liquid
  • Not to be chewed or crushed
  • Absorption not affected by food
  • Can be taken before, during, or after a meal

Interaction

  • Concomitant diuretic administration risk
  • Risk with potassium sparing diuretics
  • Concomitant therapy with lithium risk
  • Alcohol exacerbation risk
  • NSAIDs interference risk

Contraindications

  • Hypersensitivity
  • Angioedema history
  • Sacubitril/valsartan concomitant therapy
  • Renal artery stenosis
  • Hypotensive states
  • Aliskiren-containing medicines concomitant therapy
  • Angiotensin II receptor antagonists concomitant therapy
  • Pregnancy
  • ACE inhibitors and extracorporeal treatments avoidance

Side Effects

  • Dizziness
  • Headache
  • Fatigue
  • Asthenia
  • Symptomatic hypotension
  • Cough
  • Nausea
  • Vomiting
  • Diarrhea
  • Rash
  • Urticaria
  • Oliguria
  • Anxiety
  • Amnesia
  • Angioneurotic edema
  • Anaphylactic reactions
  • Hyperkalemia

Pregnancy & Lactation

  • Pregnancy exclusion
  • Avoidance of pregnancy during treatment
  • Discontinuation during pregnancy
  • Breastfeeding avoidance

Precautions & Warnings

  • Caution in impaired renal function
  • Caution in hyperkalaemia
  • Caution in hypotension
  • Caution in impaired hepatic function

Use in Special Populations

  • Elderly use caution
  • Hepatic impairment caution
  • Renal impairment caution
  • Patients pretreated with a diuretic caution

Overdose Effects

  • Excessive peripheral vasodilatation
  • Marked hypotension
  • Bradycardia
  • Electrolyte disturbances
  • Renal failure
  • Primary detoxification
  • Administration of adsorbents
  • Volume and salt substitution

Therapeutic Class

  • ACE inhibitors

Storage Conditions

  • Store at 30°C or below
  • Protect from light
  • Dispense on prescription of a registered physician

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