Reladol 100 mg/2 ml (IM/IV Injection)

2 ml ampoule: ৳ 20.00 (1 x 5: ৳ 100.00)

Medicine Details

Category	Details
Generic	Tramadol hydrochloride
Company	Globe pharmaceuticals ltd

Indications

Postoperative pain
Colic and spastic pain
Cancer pain
Joint pain
Neck and back pain
Pain associated with osteoporosis

Pharmacology

Centrally acting synthetic analgesic compound. Inhibits reuptake of neurotransmitters- serotonin and noradrenaline. Modifies transmission of pain impulses by activating serotonergic pathways and noradrenergic pathways. Mediated via stimulation of mu-opioid receptors and indirect modulation of central monoaminergic inhibitory pathways.

Dosage & Administration

Usual doses: 50 to 100 mg every 4-6 hours
Initial dose for acute pain: 100 mg
Initial dose for chronic painful conditions: 50 mg
Sustained Release Capsule or Tablet: one every 12 hours
Injection: 50-100 mg every 4-6 hours
Suppository for adults: 100 mg every 6 hours

Interaction

Contraindicated with monoamine oxidase inhibitors. Carbamazepine may increase metabolism.

Contraindications

Hypersensitivity to Tramadol. Acute intoxication with alcohol, hypnotics, centrally acting analgesics, opioids or psychotropic drugs.

Side Effects

Dizziness/vertigo
Nausea
Constipation
Headache
Somnolence
Vomiting
Pruritus
CNS stimulation
Asthenia
Sweating
Dyspepsia
Dry mouth
Diarrhoea

Pregnancy & Lactation

Safe use not established in pregnancy. Tramadol crosses placenta. Not recommended during breastfeeding.

Precautions & Warnings

Respiratory depression risk
Not recommended for opioid-dependent patients
Caution with concomitant CNS depressants
Caution with concomitant MAO inhibitors
Caution with increased intracranial pressure or head injury

Use in Special Populations

Children from 1 year: 1-2 mg/kg body weight. Avoid suppository in children under 14 years.