Pavigard 2 mg (Tablet)

Unit Price: ৳ 10.00 (2 x 10: ৳ 200.00)
Strip Price: ৳ 100.00

Medicine Details

Category Details
Generic Pitavastatin calcium
Company Acme laboratories ltd

Indications

  • Reduction of elevated total cholesterol (TC)
  • Reduction of low-density lipoprotein cholesterol (LDL-C)
  • Increase of high-density lipoprotein cholesterol (HDL-C)
  • Reduction of apolipoprotein B (Apo B)
  • Reduction of triglycerides (TG)
  • Adjunctive therapy to diet for primary hyperlipidemia
  • Adjunctive therapy to diet for mixed dyslipidemia

Pharmacology

  • Inhibition of HMG-CoA reductase
  • Lowering of plasma cholesterol levels
  • Lowering of lipoprotein levels
  • Enhanced uptake and catabolism of LDL

Dosage & Administration

  • Oral administration
  • Dose range: 1-4 mg once daily
  • Recommended starting dose: 2 mg
  • Maximum dose: 4 mg
  • Lipid levels analysis after 4 weeks

Dosage in Patients with Renal Impairment

  • Starting dose: 1 mg once daily
  • Maximum dose: 2 mg once daily
  • Not recommended for severe renal impairment

Interaction

  • Contraindicated with cyclosporine
  • Elevated exposure with erythromycin
  • Elevated exposure with rifampin
  • Caution with concomitant use of fibrates
  • No significant interaction with warfarin

Contraindications

  • Hypersensitivity to any component
  • Known hypersensitivity reactions including rash, pruritus, and urticaria
  • Active liver disease

Side Effects

  • Rhabdomyolysis
  • Myopathy
  • Liver enzyme abnormalities

Pregnancy & Lactation

  • Pregnancy Category X
  • Contraindicated in women who are or may become pregnant
  • Unknown excretion in human milk

Precautions & Warnings

  • Use with caution in patients with predisposing factors for myopathy
  • Increase in serum transaminases reported
  • Transient elevations resolved on continued therapy or after brief interruption

Overdose Effects

  • No known specific treatment for overdose
  • Symptomatic treatment
  • Supportive measures required
  • Hemodialysis unlikely to be beneficial

Therapeutic Class

  • Other Anti-anginal & Anti-ischaemic drugs
  • Statins

Storage Conditions

  • Store in a cool and dry place
  • Protect from light & moisture
  • Keep out of the reach of children

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