Tofacent 10 mg (Tablet)
Unit Price: ৳ 70.00 (2 x 10: ৳ 1,400.00)
Strip Price: ৳ 700.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Tofacitinib |
| Company | Incepta pharmaceuticals ltd |
| Also available as |
Indications
- Rheumatoid Arthritis
- Psoriatic Arthritis
- Ulcerative Colitis
Pharmacology
Autoimmune disease medication targeting pro-inflammatory cytokines and janus kinase signalling pathway
Dosage & Administration
- Tofacitinib 5 mg twice daily
- Tofacitinib 11 mg once daily
- Tofacitinib 10 mg twice daily for ulcerative colitis
Interaction
- Potent inhibitors of Cytochrome P450 3A4 (CYP3A4)
- Moderate inhibition of CYP3A4 and potent inhibition of CYP2C19
- Potent CYP inducers
Side Effects
Common adverse reactions include upper respiratory tract infections, headache, diarrhea, and nasopharyngitis
Pregnancy & Lactation
Pregnancy Category C, potential excretion in human milk
Precautions & Warnings
- Avoid use during serious infection
- Caution for gastrointestinal perforations
- Recommended laboratory monitoring
- Avoid live vaccines
- Do not initiate if certain blood counts are low
Use in Special Populations
- Pediatric Use safety and effectiveness not established
- Caution for treating elderly
- Dosage adjustment for renal or hepatic impairment
Therapeutic Class
Immunosuppressant
Storage Conditions
Store below 30°C, protect from light and moisture, keep out of reach of children