Sucramax 1 gm/5 ml (Oral Suspension)

Indications

• Duodenal ulcer
• Gastric ulcer
• Chronic gastritis
• Prophylaxis of gastrointestinal hemorrhage from stress ulceration in seriously ill patients

Pharmacology

• Non-systemic drug
• Minimally absorbed from the gastrointestinal tract
• Promotes healing of ulcers by forming a protective barrier
• Inhibits pepsin and bile action

Dosage

• Usual dose for adults: 2 gm twice daily or 1 gm four times a day
• Maximum daily dose: 8 gm
• Pediatric population safety and efficacy not established
• No special dosage requirements for elderly patients

Administration

• Should be taken on an empty stomach
• Antacid should not be administered within 30 minutes of Sucralfate

Interaction

• May reduce bioavailability of certain drugs like Fluoroquinolones, Tetracycline, Ketoconazole, etc.
• Separate administration from other agents when critical for bioavailability
• Not to be co-administered with citrate preparations

Contraindications

• Contraindicated in patients with hypersensitivity to sucralfate

Side Effects

• Common adverse events: headache, nausea, abdominal pain, constipation, diarrhea, urticaria
• Bezoars reported in patients with underlying medical conditions or receiving enteral tube feedings
• Episodes of hyperglycemia reported in diabetic patients

Pregnancy & Lactation

• Safety not established in pregnant women
• Caution advised during breastfeeding

Precautions & Warnings

• Use with caution in patients with renal dysfunction
• Not recommended for individuals on dialysis
• Periodic laboratory testing recommended for patients with renal impairment
• Bezoars reported mainly in severely ill patients in ICU
• Dose adjustments not necessary for elderly patients

Use in Special Populations

• Not recommended for use in children under 14 years of age due to insufficient data on safety and efficacy
• Dose adjustments not necessary for elderly patients
• Use with caution in renal insufficiency patients

Overdose Effects

• Most cases of overdose remained asymptomatic
• Symptoms of abdominal pain, nausea, and vomiting reported in few cases
• Minimal risk associated with overdose

Therapeutic Class

• Chelating complex

Storage Conditions

• Store in a cool and dry place, protected from light

Related Brands

• Gastalfet 1 gm/5 ml (Oral Suspension) - beximco-pharmaceuticals-ltd
• Protecto 1 gm/5 ml (Oral Suspension) - eskayef-pharmaceuticals-ltd
• Sulafate 1 gm/5 ml (Oral Suspension) - one-pharma-ltd
• Ulsil 1 gm/5 ml (Oral Suspension) - beacon-pharmaceuticals-plc