Pregaben 100 mg/5 ml (Oral Solution)

100 ml bottle: ৳ 225.00

Medicine Details

Category Details
Generic Pregabalin
Company Incepta pharmaceuticals ltd
Also available as
Pregaben 50 mg capsule Pregaben 75 mg capsule Pregaben 150 mg capsule Pregaben 25 mg capsule Pregaben cr 825 mg tablet Pregaben cr 165 mg tablet

Indications

  • Neuropathic pain associated with diabetic peripheral neuropathy (DPN)
  • Postherpetic neuralgia (PHN)
  • Adjunctive therapy for the treatment of partial-onset seizures in patients 1 month of age and older
  • Fibromyalgia
  • Neuropathic pain associated with spinal cord injury

Pharmacology

  • Structural derivative of inhibitory neurotransmitter gamma-aminobutyric acid (GABA)
  • Binds with high affinity to the alpha2-delta site in central nervous system tissues

Dosage

  • Maximum recommended dose for diabetic peripheral neuropathy: 100 mg three times a day
  • Maximum recommended dose for fibromyalgia: 300 to 450 mg/day
  • Dosage form: Pregabalin tablet and Pregabalin CR capsule
  • Route of administration: Oral
  • Dosage adjustment based on individual patient response and tolerability

Administration

  • Pregabalin CR tablet should be administered after an evening meal
  • Swallowed whole and should not be split, crushed, or chewed
  • Gradual tapering when discontinuing both Pregabalin and Pregabalin CR over a minimum of 1 week

Interaction

  • Unlikely to be involved in significant pharmacokinetic drug interactions
  • No significant drug interaction with food and others

Contraindications

  • Contraindicated in patients with known hypersensitivity to Pregabalin or any of its components

Side Effects

  • Common side effects in adults: dizziness, somnolence, dry mouth, edema, blurred vision, weight gain
  • Common side effects in pediatric patients: increased weight and increased appetite

Pregnancy & Lactation

  • No adequate and well-controlled studies in pregnant women
  • Small amounts detected in the milk of lactating women

Precautions & Warnings

  • Angioedema may occur and may be associated with life-threatening respiratory compromise
  • Patients need to be monitored when used with concomitant CNS depressants
  • Pregabalin may cause dizziness and somnolence impairing patients' ability to drive or operate machinery
  • Increased seizure frequency or adverse reactions may occur if Pregabalin is rapidly discontinued

Use in Special Populations

  • Safety and effectiveness in pediatric patients not established for certain indications
  • Safety and effectiveness not established in pediatric patients below the age of 1 month

Overdose Effects

  • Signs and symptoms: reduced consciousness, depression/anxiety, seizures
  • No specific antidote
  • General supportive care indicated including monitoring of vital signs

Therapeutic Class

  • Adjunct anti-epileptic drugs
  • Primary anti-epileptic drugs

Storage Conditions

  • Keep in a cool and dry place (below 30°C)
  • Protected from light and moisture
  • Keep out of the reach of children

Chemical Structure

  • Molecular Formula: C8H17NO2

Common Questions

  • What is Pregaben 100 mg/5 ml Solution?
  • How long do I need to use Pregaben 100 mg/5 ml Solution before I see improvement in my condition?
  • At what frequency do I need to use Pregaben 100 mg/5 ml Solution?
  • Should I use Pregaben 100 mg/5 ml Solution empty stomach, before food or after food?
  • What are the instructions for the storage and disposal of Pregaben 100 mg/5 ml Solution?
  • Does Pregaben 100 mg/5 ml Solution work in the same way for each disease?
  • How long do I need to take Pregaben 100 mg/5 ml Solution?
  • Is it necessary to continue taking Pregaben 100 mg/5 ml Solution even if I feel fine?
  • Can I take Diazepam and Pregaben 100 mg/5 ml Solution together?
  • Can the use of Pregaben 100 mg/5 ml Solution cause weight gain?
  • Quick Tips for using Pregaben 100 mg/5 ml Solution

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