Pregaben 100 mg/5 ml (Oral Solution)
100 ml bottle: ৳ 225.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Pregabalin |
| Company | Incepta pharmaceuticals ltd |
| Also available as |
Indications
- Neuropathic pain associated with diabetic peripheral neuropathy (DPN)
- Postherpetic neuralgia (PHN)
- Adjunctive therapy for the treatment of partial-onset seizures in patients 1 month of age and older
- Fibromyalgia
- Neuropathic pain associated with spinal cord injury
Pharmacology
- Structural derivative of inhibitory neurotransmitter gamma-aminobutyric acid (GABA)
- Binds with high affinity to the alpha2-delta site in central nervous system tissues
Dosage
- Maximum recommended dose for diabetic peripheral neuropathy: 100 mg three times a day
- Maximum recommended dose for fibromyalgia: 300 to 450 mg/day
- Dosage form: Pregabalin tablet and Pregabalin CR capsule
- Route of administration: Oral
- Dosage adjustment based on individual patient response and tolerability
Administration
- Pregabalin CR tablet should be administered after an evening meal
- Swallowed whole and should not be split, crushed, or chewed
- Gradual tapering when discontinuing both Pregabalin and Pregabalin CR over a minimum of 1 week
Interaction
- Unlikely to be involved in significant pharmacokinetic drug interactions
- No significant drug interaction with food and others
Contraindications
- Contraindicated in patients with known hypersensitivity to Pregabalin or any of its components
Side Effects
- Common side effects in adults: dizziness, somnolence, dry mouth, edema, blurred vision, weight gain
- Common side effects in pediatric patients: increased weight and increased appetite
Pregnancy & Lactation
- No adequate and well-controlled studies in pregnant women
- Small amounts detected in the milk of lactating women
Precautions & Warnings
- Angioedema may occur and may be associated with life-threatening respiratory compromise
- Patients need to be monitored when used with concomitant CNS depressants
- Pregabalin may cause dizziness and somnolence impairing patients' ability to drive or operate machinery
- Increased seizure frequency or adverse reactions may occur if Pregabalin is rapidly discontinued
Use in Special Populations
- Safety and effectiveness in pediatric patients not established for certain indications
- Safety and effectiveness not established in pediatric patients below the age of 1 month
Overdose Effects
- Signs and symptoms: reduced consciousness, depression/anxiety, seizures
- No specific antidote
- General supportive care indicated including monitoring of vital signs
Therapeutic Class
- Adjunct anti-epileptic drugs
- Primary anti-epileptic drugs
Storage Conditions
- Keep in a cool and dry place (below 30°C)
- Protected from light and moisture
- Keep out of the reach of children
Chemical Structure
- Molecular Formula: C8H17NO2
Common Questions
- What is Pregaben 100 mg/5 ml Solution?
- How long do I need to use Pregaben 100 mg/5 ml Solution before I see improvement in my condition?
- At what frequency do I need to use Pregaben 100 mg/5 ml Solution?
- Should I use Pregaben 100 mg/5 ml Solution empty stomach, before food or after food?
- What are the instructions for the storage and disposal of Pregaben 100 mg/5 ml Solution?
- Does Pregaben 100 mg/5 ml Solution work in the same way for each disease?
- How long do I need to take Pregaben 100 mg/5 ml Solution?
- Is it necessary to continue taking Pregaben 100 mg/5 ml Solution even if I feel fine?
- Can I take Diazepam and Pregaben 100 mg/5 ml Solution together?
- Can the use of Pregaben 100 mg/5 ml Solution cause weight gain?
- Quick Tips for using Pregaben 100 mg/5 ml Solution