Corestin 10 mg (Tablet)

Unit Price: ৳ 25.00 (3 x 10: ৳ 750.00)
Strip Price: ৳ 250.00

Medicine Details

Title

  • Corestin 10 mg Tablet

Categories

  • Medicine
  • Pharmaceuticals
  • Healthcare

Description

  • Selective and competitive inhibitor of HMG-CoA reductase
  • Indicated for Heterozygous Hypercholesterolemia, Homozygous Hypercholesterolemia, Mixed Dyslipidemia, Primary prevention of cardiovascular disease

Indications

  • Heterozygous Hypercholesterolemia (Familial and Non familial)
  • Homozygous Hypercholesterolemia (Familial)
  • Mixed Dyslipidemia (Fredrickson Type IIa and IIb)
  • Primary prevention of cardiovascular disease

Pharmacology

  • Selective and competitive inhibitor of HMG-CoA reductase
  • Increases hepatic LDL receptors
  • Inhibits hepatic synthesis of VLDL and LDL particles

Dosage

  • Dose range: 5-40 mg once daily
  • Starting dose: 20 mg/day for HoFH
  • Pediatric patients: 5-10 mg/day for 8 to less than 10 years age, 5-20 mg/day for 10 to 17 years of age

Administration

  • Can be taken with or without food, at any time of day

Interaction

  • Cyclosporine: Combination increases exposure, dose limited to 5 mg once daily
  • Gemfibrosil: Combination should be avoided, if used together dose limited to 10 mg once daily
  • Lopinavir/Ritonavir or atazanavir/ritonavir: Combination increases exposure, dose limited to 10 mg once daily
  • Coumarin anticoagulants: Combination prolongs international normalized ratio (INR), requires frequent monitoring

Contraindications

  • Known hypersensitivity to product components
  • Liver disease
  • Pregnant women and women who may become pregnant
  • Nursing mothers

Side effects

  • Headache
  • Myalgia
  • Constipation
  • Asthenia
  • Abdominal pain
  • Nausea

Precautions warnings

  • Skeletal muscle effects (e.g., myopathy and rhabdomyolysis)
  • Liver enzyme abnormalities and monitoring
  • Use in children not established

Storage conditions

  • Keep below 30°C temperature
  • Protected from light & moisture
  • Keep out of the reach of children

Chemical structure

  • Molecular formula: C22H28FN3O6S
  • Chemical structure image: https://medex.com.bd/storage/res/g-res-970-rosuvastatin-calcium-chemical-structure-UjXgzBvpDHiLnIP3gZua.svg

Common questions

  • What is Corestin 10 mg Tablet?
  • What are the uses of Corestin 10 mg Tablet?
  • What are the side effects of Corestin 10 mg Tablet?
  • For how long should I take Corestin 10 mg Tablet?
  • Does Corestin 10 mg Tablet cause weight gain?
  • Does Corestin 10 mg Tablet make you tired?
  • Should Corestin 10 mg Tablet be taken at night?
  • What foods should be avoided when taking Corestin 10 mg Tablet?
  • How do I know whether Corestin 10 mg Tablet is beneficial for me or not?
  • Can Corestin 10 mg Tablet cause memory loss?
  • Is it true that Corestin 10 mg Tablet can cause diabetes?
  • Can I take alcohol with Corestin 10 mg Tablet?
  • Can Corestin 10 mg Tablet cause muscle problems or muscle injury?

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