Telmidip 10 mg+80 mg (Tablet)

Unit Price: ৳ 13.00 (3 x 10: ৳ 390.00)
Strip Price: ৳ 130.00

Medicine Details

Indications

  • Treatment of hypertension
  • Initial therapy for blood pressure goals

Pharmacology

  • Fixed dose combination of Telmisartan and Amiodipine
  • Angiotensin II antagonist
  • Vasoconstrictor and aldosterone-secreting effects blockage
  • Inhibition of calcium ion influx into vascular smooth muscle and cardiac muscle

Dosage & Administration

  • Usual starting dose: 40/5 mg once daily
  • Patients requiring larger blood pressure reductions may be started with 80/5 mg once daily
  • Maximum recommended dose: 80/10 mg once daily

Interaction

  • No clinically significant interaction with acetaminophen, glyburide, simvastatin, hydrochlorothiazide, warfarin, or ibuprofen
  • Safely administered with various drugs such as thiazide diuretics, beta-blockers, and antibiotics

Contraindications

  • Known hypersensitivity to the product or its components
  • Pregnancy & lactation
  • Severe hepatic impairment, hypotension, cardiogenic shock, left ventricle outflow tract obstruction

Side Effects

  • Dizziness
  • Peripheral edema
  • Migraine
  • Bradycardia
  • Palpitations
  • Hypotension
  • Cough
  • Abdominal pain
  • Fatigue

Pregnancy & Lactation

  • Pregnancy Categories C and D
  • Discontinue nursing if adverse effects on the infant
  • Consider the importance of the drug to the mother

Precautions & Warnings

  • Avoid fetal or neonatal exposure
  • Correct volume or salt depletion before therapy
  • Monitor for worsening heart failure
  • Avoid concomitant use of ACE inhibitor and angiotensin receptor blocker

Use in Special Populations

  • Pediatric use not established
  • Not recommended in patients ≥75 years old
  • Not recommended in hepatically impaired patients

Overdose Effects

  • Manifestations of overdose: hypotension, dizziness, tachycardia
  • Amiodipine overdosage may cause excessive peripheral vasodilation
  • Supportive treatment should be instituted if symptomatic hypotension occurs

Therapeutic Class

  • Combined antihypertensive preparations

Storage Conditions

  • Do not store above 30°C
  • Protect from light and high humidity
  • Keep out of the reach of children

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