Fixonase 27.5 mcg/spray (Nasal Spray)
120 metered sprays: ৳ 275.00
Medicine Details
Category | Details |
---|---|
Generic | Fluticasone furoate |
Company | Beximco pharmaceuticals ltd |
Indications
- Seasonal allergic rhinitis treatment
- Perennial allergic rhinitis treatment
- Asthma maintenance treatment
- Prophylactic therapy for asthma
- Asthma control without bronchospasm relief
Description
- Synthetic fluorinated corticosteroid
- Topical administration
- Aqueous suspension
- Microfine Fixonase particles
- Metering and atomizing spray pump
- Priming instructions
- 120 metered sprays per bottle
- Bottle disposal after 120 sprays
Pharmacology
- Trifluorinated corticosteroid
- Potent anti-inflammatory activity
- Actions on multiple cell types
- Effects on various mediators
- Wide range of anti-inflammatory actions
Dosage
- Dosage for adults and children over 12 years
- Variable dosage for children aged 2-11 years
- No data for children under 2 years
- Dosage for asthma severity
- Usual starting dose for adults and adolescents
- Dosage adjustment for inadequate asthma control
- Pediatric dosage for children aged 5-11 years
Administration
- Nasal spray usage instructions
- Nasal spray cleaning procedures
Interaction
- Increase in exposure with CYP3A4 inhibitors
- Cautions with ritonavir coadministration
- Device priming instructions
Contraindications
- Hypersensitivity to ingredients
Side Effects
- Limited systemic absorption
- Less systemic side effects
- Potential nasal dryness
- Increased nosebleed incidence
- Common adverse reactions in adults and adolescents
- Common adverse reactions in pediatric subjects
Pregnancy & Lactation
- Pregnancy category C
- Use only if benefit justifies risk
- Possibility of excretion in breast milk
- Caution in nursing women
Precautions & Warnings
- Rare hypersensitivity reactions
- Rare immediate reactions
- Risk of contact dermatitis
- Rare occurrence of wheezing
- Potential nasal septum perforation
- Reported instances of cataracts
- Reported instances of glaucoma
- Minimal systemic effects with recommended doses
- Risk increase with larger doses
- Avoidance of larger than recommended doses
Use in Special Populations
- Cautious dose selection for elderly patients
- Consideration for decreased hepatic, renal, or cardiac function
- Consideration for concomitant disease or drug therapy
- Caution in severe hepatic impairment
- No dosage adjustment in renal impairment
Therapeutic Class
- Nasal steroid preparations
Storage Conditions
- Temperature not exceeding 30°C
- Avoid refrigeration
- Protection from light and moisture
- Keep out of reach of children