Fixonase 27.5 mcg/spray (Nasal Spray)

120 metered sprays: ৳ 275.00

Medicine Details

Indications

  • Seasonal allergic rhinitis treatment
  • Perennial allergic rhinitis treatment
  • Asthma maintenance treatment
  • Prophylactic therapy for asthma
  • Asthma control without bronchospasm relief

Description

  • Synthetic fluorinated corticosteroid
  • Topical administration
  • Aqueous suspension
  • Microfine Fixonase particles
  • Metering and atomizing spray pump
  • Priming instructions
  • 120 metered sprays per bottle
  • Bottle disposal after 120 sprays

Pharmacology

  • Trifluorinated corticosteroid
  • Potent anti-inflammatory activity
  • Actions on multiple cell types
  • Effects on various mediators
  • Wide range of anti-inflammatory actions

Dosage

  • Dosage for adults and children over 12 years
  • Variable dosage for children aged 2-11 years
  • No data for children under 2 years
  • Dosage for asthma severity
  • Usual starting dose for adults and adolescents
  • Dosage adjustment for inadequate asthma control
  • Pediatric dosage for children aged 5-11 years

Administration

  • Nasal spray usage instructions
  • Nasal spray cleaning procedures

Interaction

  • Increase in exposure with CYP3A4 inhibitors
  • Cautions with ritonavir coadministration
  • Device priming instructions

Contraindications

  • Hypersensitivity to ingredients

Side Effects

  • Limited systemic absorption
  • Less systemic side effects
  • Potential nasal dryness
  • Increased nosebleed incidence
  • Common adverse reactions in adults and adolescents
  • Common adverse reactions in pediatric subjects

Pregnancy & Lactation

  • Pregnancy category C
  • Use only if benefit justifies risk
  • Possibility of excretion in breast milk
  • Caution in nursing women

Precautions & Warnings

  • Rare hypersensitivity reactions
  • Rare immediate reactions
  • Risk of contact dermatitis
  • Rare occurrence of wheezing
  • Potential nasal septum perforation
  • Reported instances of cataracts
  • Reported instances of glaucoma
  • Minimal systemic effects with recommended doses
  • Risk increase with larger doses
  • Avoidance of larger than recommended doses

Use in Special Populations

  • Cautious dose selection for elderly patients
  • Consideration for decreased hepatic, renal, or cardiac function
  • Consideration for concomitant disease or drug therapy
  • Caution in severe hepatic impairment
  • No dosage adjustment in renal impairment

Therapeutic Class

  • Nasal steroid preparations

Storage Conditions

  • Temperature not exceeding 30°C
  • Avoid refrigeration
  • Protection from light and moisture
  • Keep out of reach of children

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