Akno 10 mg (Capsule)
Unit Price: ৳ 40.00 (1 x 15: ৳ 600.00)
Strip Price: ৳ 600.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Isotretinoin oral |
| Company | Drug international ltd |
Indications
- Severe forms of acne
- Nodular acne
- Conglobate acne
- Acne at risk of scarring
- Resistant to standard therapies
Pharmacology
- Alters cell cycle
- Reduces sebum production
- Prevents pore blockage
- Reduces growth of acne causing bacteria
- Induces apoptosis in sebocytes
Dosage & Administration
- Take with food
- Prescribed by physicians with expertise
- Start with 0.5mg/kg daily
- Individual dosage adjustment
- Therapeutic response is dose-related
- Duration of treatment 16-24 weeks
Interaction
- Additive adverse effects with vit A
- Decreased efficacy with progesterone
- Increased risk of local irritation with keratolytic agents
- Reduced efficacy with oxidizing agents
Contraindications
- Contraindicated in pregnant or breastfeeding women
- Contraindicated in patients with hypersensitivity
- Contraindicated in patients with hepatic insufficiency
- Contraindicated in patients with hypervitaminosis A
Side Effects
- Dryness of the skin
- Dryness of the mucosae
- Epistaxis
- Anaemia
- Headache
- Depression
- Pruritus
- Rash
- Arthralgia
- Hepatitis
Pregnancy & Lactation
- Absolute contraindication in pregnancy
- Increased risk of severe foetal malformations
- Contraindicated in nursing mothers
Precautions & Warnings
- Comprehensive information on pregnancy prevention
- Medically supervised pregnancy tests
- Follow-up visits at 28 day intervals
- Limit prescriptions to 30 days for women of childbearing potential
- Contraceptive advice for female patients
- Monitoring for signs of depression
- Avoid exposure to intense sunlight
- Check liver enzymes and lipid levels before and during treatment
Therapeutic Class
- Oral retinoids for acne
Storage Conditions
- Keep below 30°C
- Away from light & moisture
- Keep out of the reach of children