Nestor 5 mg (Tablet)

Unit Price: ৳ 10.03 (3 x 10: ৳ 300.90)
Strip Price: ৳ 100.30

Medicine Details

Category Details
Generic Rosuvastatin calcium
Company Navana pharmaceuticals ltd
Also available as
Nestor 10 mg tablet

Indications

  • Heterozygous Hypercholesterolemia (Familial and Non familial)
  • Homozygous Hypercholesterolemia (Familial)
  • Mixed Dyslipidemia (Fredrickson Type IIa and IIb)
  • Primary prevention of cardiovascular disease

Pharmacology

  • Selective and competitive inhibitor of HMG-CoA reductase
  • Increases hepatic LDL receptors on the cell surface
  • Inhibits hepatic synthesis of VLDL and LDL particles

Dosage

  • Dose range: 5-40 mg once daily
  • Starting dose 20 mg/day for HoFH
  • Pediatric patients with HeFH: 5-10 mg/day for patients 8 to less than 10 years age
  • Pediatric patients with HoFH: 20 mg/day for patients 7 to 17 years of age

Administration

  • Can be taken with or without food, at any time of day

Interaction

  • Cyclosporine: Combination increases Nestor exposure. Nestor dose should be limited to 5 mg once daily
  • Gemfibrosil: Combination should be avoided. If used together, Nestor dose should be limited to 10 mg once daily
  • Lopinavir/Ritonavir or atazanavir/ritonavir: Combination increases Nestor exposure. Nestor dose should be to 10 mg once daily
  • Coumarin anticoagulants: Combination prolongs international normalized ratio (INR). Stable INR should be achieved prior to starting Nestor. INR should be monitored frequently until stable upon initiation or alteration of Nestor therapy
  • Concomitant lipid-lowering therapies: Use with fibrates and niacin products may increase the risk of skeletal muscle effects

Contraindications

  • Known hypersensitivity to product components
  • Liver disease, including unexplained persistent elevations in hepatic transaminase levels
  • Pregnant and nursing women

Side Effects

  • Headache
  • Myalgia
  • Constipation
  • Asthenia
  • Abdominal pain
  • Nausea

Pregnancy & Lactation

  • Safety in pregnant women not established
  • Excretion in human milk not established

Precautions & Warnings

  • Skeletal muscle effects risks increase with 40 mg dose, advanced age (>65 years), hypothyroidism, renal impairment, and combination use with certain drugs
  • Prompt reporting of unexplained muscle pain, tenderness or weakness
  • Monitoring of liver enzyme abnormalities

Use in Special Populations

  • Safety and effectiveness in pediatric patients not established

Therapeutic Class

  • Other Anti-anginal & Anti-ischaemic drugs
  • Statins

Storage Conditions

  • Keep below 30°C temperature, protected from light & moisture
  • Keep out of the reach of children

Chemical Structure

  • Molecular Formula : C22H28FN3O6S

Common Questions about Nestor 5 mg Tablet

  • Useful against conditions like Hyperlipidemia, Hypertriglyceridemia, Type 3 Hyperlipoproteinemia, and Stroke
  • Duration of usage should follow doctor's instructions
  • Does not cause weight gain but may lead to tiredness and fatigue
  • Should not be taken with alcohol
  • Can cause muscle problems or muscle injury

Quick Tips

  • Treats high cholesterol by lowering 'bad' cholesterol (LDL) and triglycerides
  • Safe to take with food if experiencing diarrhea, gas, or upset stomach
  • Inform doctor if experiencing fatigue, muscle weakness, or pain
  • Check liver function before and during treatment and monitor signs of liver problems
  • Inform doctor if having kidney disease, liver disease, or diabetes before starting treatment
  • Avoid if pregnant, planning pregnancy, or breastfeeding

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