Avaflut 27.5 mcg/spray (Nasal Spray)

120 metered sprays: ৳ 250.00

Medicine Details

Category Details
Generic Fluticasone furoate
Company Osl pharma limited

Indications

  • Treatment of seasonal allergic rhinitis
  • Treatment of perennial allergic rhinitis
  • Prophylactic treatment of asthma in patients aged 5 years and older

Description

  • Synthetic fluorinated corticosteroid
  • Aqueous suspension of microfine Avaflut
  • Topical administration to the nasal mucosa
  • Metering and atomizing spray pump
  • Necessary to prime the pump before first use or after a period of non-use
  • Each bottle provides 120 metered sprays

Pharmacology

  • Synthetic trifluorinated corticosteroid with potent anti-inflammatory activity
  • Wide range of actions on multiple cell types and mediators involved in inflammation

Dosage

  • Recommended dosage for adults and children over 12 years
  • Recommended dosage for children aged 2-11 years
  • Recommended dosage for children under 2 years
  • Recommended dosage for adults and adolescents aged 12 years and older with asthma
  • Starting dosage based on asthma severity
  • Highest recommended daily dose in adults and adolescents aged 12 years and older
  • Recommended dosage for pediatric patients aged 5 to 11 years

Administration

  • Instructions for using the nasal spray
  • Cleaning instructions for the nasal spray

Interaction

  • Potential interaction with potent inhibitors of cytochrome P450 3A4 (CYP3A4)
  • Cautions and instructions for priming the device

Contraindications

  • Contraindicated in patients with hypersensitivity to any of its ingredients

Side Effects

  • Less absorption into the rest of the body
  • Possible side effects of nasal spray: drying of the nose and increased incidence of nosebleeds
  • Common adverse reactions of inhalation capsule in adult and adolescent subjects
  • Common adverse reactions of inhalation capsule in pediatric subjects aged 5 to 11 years

Pregnancy & Lactation

  • Pregnancy category C
  • Use in pregnancy only if potential benefit justifies potential risk
  • Caution in lactation due to potential excretion in human breast milk

Precautions & Warnings

  • Possible hypersensitivity reactions or contact dermatitis
  • Rare instances of wheezing, nasal septum perforation, cataracts, glaucoma, and increased intraocular pressure

Use in Special Populations

  • Dose selection for the elderly patient
  • Use with caution in patients with severe hepatic impairment
  • No dosage adjustment required in patients with renal impairment

Therapeutic Class

  • Nasal steroid preparations

Storage Conditions

  • Temperature not exceeding 30°C
  • Do not refrigerate
  • Protect from light and moisture
  • Keep out of the reach of children

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