Domfix 5 mg/ml (Pediatric Drops)
15 ml drop: ৳ 25.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Domperidone maleate |
| Company | Osl pharma limited |
| Also available as |
Title and Categories
- Domfix 5 mg/ml Pediatric Drop
- Medicine
- Motility Stimulants
- Motility stimulants/Dopamine antagonist
- Prokinetic drugs
Dimensions
N/A
Color Options
N/A
Functions
- Relief of dyspeptic symptom complex
- Treatment of acute nausea and vomiting
- Speeding barium transit in radiological studies
Materials
Chemical compound: C22H24ClN5O2
Technical Specifications
- Molecular Formula: C22H24ClN5O2
- Chemical Structure: Image available
Design Elements
- Dopamine antagonist
- Gastrointestinal motility regulator
- Gastroprokinetic agent
Usability Features
- Pediatric drops
- Oral suspension
- Rectal suppositories
Dosage
- Adults: 10-20 mg (1-2 tablets or 10-20 ml suspension), every 6-8 hours daily
- Children: 2-4 ml suspension/10 kg body weight or 0.4-0.8 ml pediatric drops/10 kg body weight, every 6-8 hours daily
Administration
Oral, 15-30 minutes before meals
Indications
- Dyspeptic symptom complex
- Delayed gastric emptying
- Gastroesophageal reflux and esophagitis
- Acute nausea and vomiting
- Parkinson's disease
- Radiological studies
Pharmacology
Dopamine antagonist that blocks receptors in CTZ and stomach, promotes gastroprokinetic action, restores normal motility and tone of upper GI tract
Interaction
- Antagonism with anticholinergic drugs
- Effect on oral bioavailability when given with antacids and antisecretory drugs
- Metabolic pathway through CYP3A4
Contraindications
- Hypersensitivity to the drug
- Neonates
- Gastrointestinal hemorrhage
- Mechanical obstruction or perforation
- Prolactin releasing pituitary tumor (prolactinoma)
Side Effects
- Transient intestinal cramps
- Extrapyramidal phenomena
- Increase in plasma prolactin level
- Rare allergic reactions
Pregnancy & Lactation
- Use during first trimester if justified by therapeutic benefit
- Caution with breastfeeding due to excretion in breast milk
Precautions & Warnings
- Caution in children due to risk of extrapyramidal reactions
- Caution in hepatic impairment
Special Populations
- Use in infants under close medical supervision
- Use with caution in liver disorders
- Use with caution in severe renal insufficiency
Overdose Effects
- Drowsiness
- Disorientation
- Extrapyramidal reactions
- Recommendations for management
Storage Conditions
Store below 30°C, protected from light & moisture, keep out of children's reach
Common Questions
- Usage for nausea and vomiting
- Quick tips for usage and precautions