Loctril 5 mg (Chewable Tablet)

Unit Price: ৳ 8.00 (3 x 14: ৳ 336.00)
Strip Price: ৳ 112.00

Medicine Details

Category Details
Generic Montelukast sodium
Company Osl pharma limited
Also available as
Loctril 10 mg tablet Loctril 4 mg chewable tablet Loctril 4 mg oral granules

Indications

  • Prophylaxis and chronic treatment of asthma
  • Acute prevention of Exercise-Induced Bronchoconstriction (EIB)
  • Relief of symptoms of Allergic Rhinitis (AR): Seasonal & Perennial Allergic Rhinitis

Pharmacology

  • Montelukast is a selective and orally active leukotriene receptor antagonist
  • Inhibits the cysteinyl leukotriene receptor (CysLT1)
  • Correlated with pathophysiology of asthma & allergic rhinitis

Dosage & Administration

  • Dosage for adults and adolescents 15 years of age and older: Montelukast 10 mg tablet once daily
  • Dosage for pediatric patients 6 to 14 years of age: Montelukast 5 mg tablet once daily
  • Dosage for pediatric patients 2 years to 5 years of age: Montelukast 4 mg tablet once daily
  • Dosage for pediatric patients 6 months to 5 years of age: Montelukast 4 mg oral granules once daily
  • Hepatic Insufficiency: No dosage adjustment required
  • Renal Insufficiency: No dosage adjustment recommended
  • Elderly use: Similar pharmacokinetics as in younger adults

Interactions

  • No clinically important effects on the pharmacokinetics of certain drugs
  • Used concomitantly with a wide range of commonly prescribed drugs without evidence of clinical adverse interactions
  • Phenobarbital decreased the AUC of Loctril by approximately 40%

Contraindications

  • Hypersensitivity to any component of this product

Side Effects

  • Common: Diarrhoea, fever, gastrointestinal discomfort, headache, nausea, vomiting, skin reactions, upper respiratory tract infection
  • Uncommon: Akathisia, anxiety, arthralgia, asthenia, abnormal behavior, depression, dizziness, drowsiness
  • Rare: Angioedema, concentration impaired, disorientation, hallucination, hepatic disorders, memory loss, suicidal tendencies, tremor

Pregnancy & Lactation

  • Crosses the placenta in rats and rabbits, caution should be exercised during pregnancy and lactation

Precautions & Warnings

  • Not indicated for use in the reversal of bronchospasm in acute asthma attacks
  • Should be continued during acute exacerbations of asthma under medical supervision
  • Not to be abruptly substituted for inhaled or oral corticosteroids
  • Not to be used as monotherapy for the treatment and management of exercise induced bronchospasm
  • Patients with known aspirin sensitivity should continue avoidance of aspirin or non-steroidal anti-inflammatory agents

Overdose Effects

  • Most frequently occurring adverse experiences include abdominal pain, somnolence, thirst, headache, vomiting and psychomotor hyperactivity
  • Usual supportive measures should be employed in the event of overdose

Therapeutic Class

  • Leukotriene receptor antagonists

Storage Conditions

  • Store in cool & dry place below 30°C
  • Protect from light & moisture
  • Keep out of reach of children

Chemical Structure

  • Molecular Formula: C35H36ClNO3S

Common Questions

  • What is Loctril 5 mg Chew. Tablet?
  • What is Loctril 5 mg Chew. Tablet used for?
  • How soon can the effect of Loctril 5 mg Chew. Tablet be observed?
  • How long does the effect of Loctril 5 mg Chew. Tablet last?
  • Should I use Loctril 5 mg Chew. Tablet empty stomach?
  • What if I miss a dose of Loctril 5 mg Chew. Tablet?
  • Are there any pregnancy warnings for Loctril 5 mg Chew. Tablet?
  • General Instructions

Related Brands