Probal-DX 600 mg+400 IU (Tablet)

Unit Price: ৳ 15.00 (3 x 10: ৳ 450.00)
Strip Price: ৳ 150.00

Medicine Details

Category Details
Generic Coral calcium vitamin d3
Company Pharmasia limited
Also available as
Probal d 500 mg tablet

Indications

  • Treatment and prevention of osteoporosis
  • Treatment and prevention of osteomalacia
  • Treatment and prevention of tetany
  • Treatment and prevention of hypoparathyroidism
  • Supplement for inadequate calcium intake in childhood diet
  • Treatment and prevention of disorders of osteogenesis
  • Supplement for rickets
  • Supplement for pregnancy and lactation
  • Supplement for elderly patients
  • Treatment of pancreatitis
  • Phosphate binder in chronic renal failure

Composition

  • Each tablet contains 1250 mg Calcium Carbonate USP (Coral source)
  • Each tablet contains 500 mg of elemental Calcium
  • Each tablet contains 200 IU Vitamin D USP
  • Each DX tablet contains 1500 mg Calcium Carbonate USP
  • Each DX tablet contains 600 mg of elemental Calcium
  • Each DX tablet contains 400 IU Vitamin D USP
  • Each effervescent tablet contains 1500 mg Calcium Carbonate USP
  • Each effervescent tablet contains 600 mg of elemental Calcium
  • Each effervescent tablet contains 400 IU Vitamin D3 as Cholecalciferol USP

Pharmacology

  • Vital for a wide variety of bodily functions
  • Useful for the prevention and treatment of Osteoporosis
  • Aids in Calcium absorption from the GI tract
  • Stimulates bone formation
  • Has synergistic effects on bone growth
  • Coral Calcium sourced for better absorption
  • Vitamin D3 aids in absorption and maintaining calcium balance

Dosage & Administration

  • One tablet once or twice daily with plenty of water
  • Dissolve 1 effervescent tablet in a glass of water
  • Taking with a full stomach ensures better absorption

Interaction

  • Thiazide diuretics reduce urinary excretion of calcium
  • Systemic corticosteroids reduce calcium absorption
  • Ion exchange resins and laxatives may reduce vitamin D absorption
  • Interfere with the absorption of concomitantly administered tetracycline preparations
  • May increase the toxicity of cardiac glycosides
  • Should be administered at least three hours before bisphosphonates or sodium fluoride
  • Inhibit calcium absorption through formation of insoluble calcium salts
  • Should not be taken within two hours of eating foods high in oxalic acid and phytic acid

Contraindications

  • Hypercalcemia and hyperparathyroidism
  • Hypercalciuria and nephrolithiasis
  • Hypersensitivity to the components
  • Severe renal insufficiency
  • Concomitant digoxin therapy

Side Effects

  • Irritating to the GI tract
  • May cause constipation
  • Rarely produce hypercalcemia
  • Possible allergic reactions
  • Possible irregular heartbeats
  • Nausea, vomiting, decreased appetite, dry mouth, and drowsiness
  • Skin rash reported post Vitamin D Supplements

Pregnancy & Lactation

  • Daily intake should not exceed specified amounts
  • Reproductive toxicity with high dose of vitamin D in animals
  • Overdoses should be avoided to prevent permanent hypercalcemia
  • No indications of teratogenic effects in humans
  • Can be used during pregnancy and breastfeeding

Precautions & Warnings

  • Long-term treatment requires serum calcium level monitoring
  • Renal function should be monitored especially in elderly patients
  • Caution in patients with impairment of renal function
  • Risk of soft tissue calcification should be taken into account
  • Caution in immobilized patients with osteoporosis
  • Dose should be considered when prescribing other drugs containing vitamin D
  • Additional doses should be taken under close medical supervision

Overdose Effects

  • Can lead to hypervitaminosis D and hypercalcemia
  • Symptoms may include anorexia, thirst, nausea, vomiting, constipation, and more
  • Persistently high calcium levels may lead to irreversible renal damage

Therapeutic Class

  • Specific mineral & vitamin combined preparations

Storage Conditions

  • Store below 30°C, protect from light & moisture
  • Keep out of reach of children

Common Questions about Probal-DX 600 mg Tablet

  • Combination of calcium carbonate and vitamin D3
  • Used to prevent and treat calcium and vitamin D deficiency
  • Important for building and maintaining strong bones and teeth
  • Prevention of osteoporosis, rickets, and osteomalacia
  • Improvement of bone health in the elderly
  • Contraindications for high levels of calcium or vitamin D, kidney stones, and allergic reactions

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