Prucon 1 mg (Tablet)
Unit Price: ৳ 13.00 (2 x 10: ৳ 260.00)
Strip Price: ৳ 130.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Prucalopride succinate |
| Company | Aci limited |
| Also available as |
Indications
- Symptomatic treatment of chronic constipation in adults
Pharmacology
- Selective stimulator of 5-HT4 receptors
- No interaction with hERG channel or 5-HT1 receptors
- Stimulates motility in the GI tract by interacting with 5-HT4 receptors
Dosage & Administration
- Adults: 2 mg once daily with or without food
- Older people: Start with 1 mg once daily
Interaction
- Low interaction potential with CYP-mediated metabolism
- Weak substrate for P-glycoprotein
Contraindications
- Hypersensitivity to the active substance or excipients
- Renal impairment requiring dialysis
Side Effects
- Headache
- Gastrointestinal symptoms (abdominal pain, nausea, diarrhea)
Pregnancy & Lactation
- Not recommended during pregnancy
- Effective contraception recommended for women of childbearing potential
Precautions & Warnings
- Dose adjustment for severe renal impairment
- Caution in patients with severe hepatic impairment
- Possible reduction in efficacy of oral contraceptives
Use in Special Populations
- Dose adjustment for severe renal impairment
- No dose adjustment for mild to moderate renal impairment
- Dose adjustment for severe hepatic impairment
- No dose adjustment for mild to moderate hepatic impairment
Overdose Effects
- Symptoms may include headache, nausea, diarrhea
- No specific treatment available
Therapeutic Class
- Osmotic purgatives
Storage Conditions
- Store at room temperature, below 30°C