Prucon 2 mg (Tablet)
Unit Price: ৳ 24.00 (2 x 10: ৳ 480.00)
Strip Price: ৳ 240.00
Medicine Details
Category | Details |
---|---|
Generic | Prucalopride succinate |
Company | Aci limited |
Also available as |
Indications
- Symptomatic treatment of chronic constipation in adults
Pharmacology
- Acts as a selective stimulator of the 5-HT4 receptors
- Stimulates motility by interacting specifically with 5-HT4 receptors
Dosage & Administration
- 2 mg once daily for adults
- Start with 1 mg once daily for older people
- Should not be used in children and adolescents younger than 18 years
Interaction
- Has a low interaction potential
- Therapeutic concentrations are not expected to affect the CYP-mediated metabolism of co-medicated medicinal products
Contraindications
- Hypersensitivity to the active substance or excipients
- Renal impairment requiring dialysis
Side Effects
- Frequently reported adverse reactions include headache and gastrointestinal symptoms
- Adverse reactions occur predominantly at the start of therapy and usually disappear within a few days with continued treatment
Pregnancy & Lactation
- Not recommended during pregnancy
- Women of childbearing potential should use effective contraception during treatment
- Not recommended during breastfeeding
Precautions & Warnings
- A dose of 1 mg is recommended in subjects with severe renal impairment
- Caution should be exercised when prescribing to patients with severe hepatic impairment
- In case of severe diarrhoea, the efficacy of oral contraceptives may be reduced
- The tablets contain lactose. Patients with rare hereditary problems of galactose intolerance should not take this medicinal product
Use in Special Populations
- The dose for patients with severe renal impairment is 1 mg once daily
- No dose adjustment is required for patients with mild to moderate renal impairment
- Patients with severe hepatic impairment start with 1 mg once daily
Overdose Effects
- An overdose may result in symptoms including headache, nausea, and diarrhoea
- Specific treatment is not available for overdose
Therapeutic Class
- Osmotic purgatives
Storage Conditions
- Store at room temperature, below 30°C
- Do not remove desiccant
- Dispense in original bottle