Lotas Plus 50 mg+12.5 mg (Tablet)
Unit Price: ৳ 5.02 (30's pack: ৳ 150.60)
Medicine Details
| Category | Details |
|---|---|
| Generic | Losartan potassium hydrochlorothiazide |
| Company | Ambee pharmaceuticals ltd |
Product Title
- Lotas Plus
Category
- Medicine
- Hypertension Treatment
- Antihypertensive Preparations
Description
- Lotas Plus is indicated for the treatment of hypertension and to reduce the risk of stroke in patients with hypertension and left ventricular hypertrophy. It contains losartan and hydrochlorothiazide.
Dimensions
- N/A
Color Options
- N/A
Functions
- Treats hypertension
- Reduces risk of stroke
- Blocks the vasoconstrictor and aldosterone-secreting effects of angiotensin II
Materials
- Losartan
- Hydrochlorothiazide
Technical Specifications
- Losartan is a reversible, competitive inhibitor of the AT1 receptor
- Hydrochlorothiazide affects the renal tubular mechanisms of electrolyte reabsorption
- No significant drug-drug pharmacokinetic interactions have been found
Design Elements
- Combination of two active ingredients
- Comes in tablet form
Usability Features
- May be administered with or without food
- Can be administered with other antihypertensive agents
Dosage Instructions
- The usual starting dose of this combination is one tablet once daily
- Maximum dosage is 100/25 once daily
- Antihypertensive effect is attained within three weeks after initiation of therapy
Administration
- May be administered with other antihypertensive agents
- May be administered with or without food
Interaction
- No significant drug-drug pharmacokinetic interactions have been found
Contraindications
- Contraindicated in patients who are hypersensitive to any component of this product
- Contraindicated in patients with anuria or hypersensitivity to other sulfonamide-derived drugs
Side Effects
- Symptomatic hypotension
- Hyperkalaemia
- Angioedema
- Vertigo
- Gastro-intestinal disturbances
- Headache
- Rash
- Hepatitis
Pregnancy & Lactation
- Angiotensin-II receptor antagonists should be avoided in pregnancy unless essential
- Not recommended during breastfeeding
Precautions & Warnings
- Periodic determination of serum electrolytes should be performed at appropriate intervals
- Hypokalemia may rarely develop, especially with brisk diuresis
Use in Special Populations
- Usual regimens of therapy may be followed as long as the patient's creatinine clearance is >30 ml/min
Overdose Effects
- Hypotension and tachycardia are the likely manifestations of overdosage
- Supportive treatment should be instituted if symptomatic hypotension occurs
Therapeutic Class
- Combined antihypertensive preparations
Storage Conditions
- Do not store above 30°C
- Keep out of the reach of children