Sumetrolim (200 mg+40 mg)/5 ml (Oral Suspension)

60 ml bottle: ৳ 21.61

Medicine Details

Title

  • Cotrimoxazole Double Strength Tablet

Categories

  • Antibiotic
  • Anti-infective
  • Therapeutic Medication

Description

Cotrimoxazole is a bactericidal medication with broad-spectrum activity, used to treat respiratory, genito-urinary, and gastrointestinal tract infections, among others.

Indications

  • Respiratory tract infections
  • Genito-urinary tract infections
  • Gastro-intestinal tract infections
  • Osteomyelitis
  • Brucellosis
  • Skin infections
  • Septicaemia
  • Dysentery
  • Cholera
  • Nocardiosis

Mode of Action

Bactericidal action against gram-positive & gram-negative bacteria and some protozoa by sequential blockade of bacterial enzyme systems in the biosynthesis of folinic acid.

Dosage & Administration

  • Recommended dosages for adults and children over 12 years
  • Different dosages for mild to severe infections
  • Long-term therapy dosages
  • Specific dosages for gonorrhoea

Contraindications

  • Hypersensitivity to trimethoprim or sulphonamides
  • Megaloblastic anaemia due to folate deficiency
  • Severe liver damage
  • Blood dyscrasia
  • Severe renal insufficiency
  • Glucose 6-phosphate dehydrogenase deficiency

Side Effects

  • Crystalluria
  • Allergic reactions
  • Haemolysis
  • Thrombocytopenia
  • Neutropenia
  • Agranulocytosis
  • Malaise
  • Headache
  • Nausea
  • Vomiting

Pregnancy & Lactation

Avoid use during pregnancy and nursing due to potential passage through placenta and breast milk, leading to kernicterus.

Precautions & Warnings

  • Risk of macrocytic anaemia with prolonged full-dose treatment
  • Potential interaction with sulphonylurea drugs in diabetic patients

Therapeutic Class

Anti-diarrhoeal antimicrobial drugs, Sulphonamides & Trimethoprim

Storage Conditions

Keep below 30°C, away from light & moisture, and out of the reach of children

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