Sumetrolim (200 mg+40 mg)/5 ml (Oral Suspension)

60 ml bottle: ৳ 21.61

Medicine Details

Category	Details
Generic	Sulphamethoxazole trimethoprim
Company	Ambee pharmaceuticals ltd
Also available as	Soma ds 800 mg tablet

Title

Cotrimoxazole Double Strength Tablet

Description

Cotrimoxazole is a bactericidal medication with broad-spectrum activity, used to treat respiratory, genito-urinary, and gastrointestinal tract infections, among others.

Indications

Respiratory tract infections
Genito-urinary tract infections
Gastro-intestinal tract infections
Osteomyelitis
Brucellosis
Skin infections
Septicaemia
Dysentery
Cholera
Nocardiosis

Mode of Action

Bactericidal action against gram-positive & gram-negative bacteria and some protozoa by sequential blockade of bacterial enzyme systems in the biosynthesis of folinic acid.

Dosage & Administration

Recommended dosages for adults and children over 12 years
Different dosages for mild to severe infections
Long-term therapy dosages
Specific dosages for gonorrhoea

Contraindications

Hypersensitivity to trimethoprim or sulphonamides
Megaloblastic anaemia due to folate deficiency
Severe liver damage
Blood dyscrasia
Severe renal insufficiency
Glucose 6-phosphate dehydrogenase deficiency

Side Effects

Crystalluria
Allergic reactions
Haemolysis
Thrombocytopenia
Neutropenia
Agranulocytosis
Malaise
Headache
Nausea
Vomiting

Pregnancy & Lactation

Avoid use during pregnancy and nursing due to potential passage through placenta and breast milk, leading to kernicterus.

Precautions & Warnings

Risk of macrocytic anaemia with prolonged full-dose treatment
Potential interaction with sulphonylurea drugs in diabetic patients

Therapeutic Class

Anti-diarrhoeal antimicrobial drugs, Sulphonamides & Trimethoprim

Storage Conditions

Keep below 30°C, away from light & moisture, and out of the reach of children