Sizolex 2 mg (Tablet)
Unit Price: ৳ 5.00 (50's pack: ৳ 250.00)
Medicine Details
| Category | Details |
|---|---|
| Generic | Risperidone oral |
| Company | The white horse pharmaceuticals ltd |
| Also available as |
Indications
- Treatment of acute and chronic psychoses
- Treatment of mania
- Treatment of schizophrenia
Pharmacology
- Selective monoaminergic antagonist
- High affinity for serotoninergic 5-HT2 and dopaminergic D2 receptors
- Binds to alpha1 adrenergic receptors
- Binds with lower affinity to H1 histamine and alpha2 adrenergic receptors
- Balanced central serotonin and dopamine antagonism
Dosage and administration
- Initial dose of 2mg in 1-2 divided doses on the first day
- Usual dose range of 4-6mg daily
- Elderly or in hepatic or renal impairment: initial dose of 1mg daily in two divided doses
Interaction
- May antagonize the effects of levodopa and dopamine agonists
- Chronic administration with Carbamazepine reduces plasma clearance
- Chronic administration with Clozapine may decrease the clearance
- May enhance the effects of certain antihypertensives
Contraindications
- Known hypersensitivity to the product
Side effects
- Insomnia
- Agitation
- Anxiety
- Headache
- Drowsiness
- Impaired concentration
- Fatigue
- Blurred vision
- Constipation
- Nausea and vomiting
- Dyspepsia
- Abdominal pain
- Hyperprolactinaemia
- Urine incontinence
- Tachycardia
- Hypertension
- Edema
- Rash
- Rhinitis
Pregnancy and lactation
- No established safety in human pregnancy
- Not recommended for breastfeeding women
Precautions and warnings
- Preexisting cardiovascular diseases
- Discontinue use if signs and symptoms of tardive dyskinesia occur
- Renal and hepatic impairment
- Elderly epilepsy
- Parkinson's disease
Therapeutic class
- Atypical neuroleptic drugs
Storage conditions
- Do not store above 30°C
- Keep away from light
- Keep out of the reach of children