Quetolex 25 mg (Tablet)
Unit Price: ৳ 3.00 (50's pack: ৳ 150.00)
Medicine Details
| Category | Details |
|---|---|
| Generic | Quetiapine fumarate |
| Company | The white horse pharmaceuticals ltd |
| Also available as |
Indications
- Treatment of Acute and chronic psychoses
- Schizophrenia
- Bipolar Disorder
- Manic episodes
- Depressive episodes
- Maintenance treatment of bipolar I disorder
- Prevention of recurrence of manic, depressive or mixed episodes
Pharmacology
- Atypical psychotropic agent
- Dibenzothiazepine derivatives
- Antagonist at multiple neurotransmitter receptors
- Unknown mechanism of action
- Dopamine D2 and serotonin 5HT2 antagonism
Dosage & Administration
- Administered twice daily
- Administered once daily at bedtime
- Dosing titration for different indications
- Dosage adjustments based on clinical response
Interaction
- Caution with medicines causing electrolyte imbalance
- Co-administration effects with thioridazine or carbamazepine
- Effects with microsomal enzyme inducers
Contraindications
- Hypersensitivity
Side Effects
- Somnolence
- Dizziness
- Dry mouth
- Withdrawal symptoms
- Elevations in serum triglyceride levels
- Weight gain
- Extrapyramidal symptoms
Pregnancy & Lactation
- Safety and efficacy during human pregnancy not established
- Caution for breastfeeding women
Precautions & Warnings
- Risk of suicidal thoughts
- Caution in patients with cardiovascular disease
- Caution in patients with history of seizures
- Consideration of tardive dyskinesia and EPS
- Potential for neuroleptic malignant syndrome
- Caution in patients with family history of QT prolongation
- Risk of neutropenia
- Potential for hyperglycemia & diabetes mellitus
Use in Special Populations
- Caution in the elderly
- Not indicated for use in children and adolescents below 18 years
Overdose Effects
- Survival reported in acute overdoses up to 30 grams
- No specific antidote
- Intensive care procedures recommended
- Refractory hypotension treatment
Therapeutic Class
- Atypical neuroleptic drugs
Storage Conditions
- Keep out of the reach of children
- Do not use after expiry date
- Store in a cool and dry place away from light