Quetolex 100 mg (Tablet)
Unit Price: ৳ 10.00 (50's pack: ৳ 500.00)
Medicine Details
| Category | Details |
|---|---|
| Generic | Quetiapine fumarate |
| Company | The white horse pharmaceuticals ltd |
| Also available as |
Indications
- Treatment of acute and chronic psychoses
- Treatment of schizophrenia
- Treatment of Bipolar Disorder
- Maintenance treatment of bipolar I disorder
Pharmacology
- Atypical psychotropic agent
- Antagonist at multiple neurotransmitter receptors
- Belongs to the dibenzothiazepine derivatives chemical class
- Antagonism of dopamine D2 and serotonin 5HT2 receptors
- Antagonism of histamine H1 receptors
Dosage & Administration
- Administered twice daily
- First four days dose titration
- Usual effective dose range
- Dosage adjustments for manic episodes and depressive episodes
- Combination therapy with a mood stabilizer
Interaction
- Caution with medicines causing electrolyte imbalance
- Caution with medicines increasing QT interval
- Co-administration with thioridazine or carbamazepine
- Co-administration with microsomal enzyme inducers
Contraindications
- Hypersensitivity to Quetiapine
Side Effects
- Somnolence
- Dizziness
- Dry mouth
- Elevations in serum triglyceride levels
- Weight gain
- Extrapyramidal symptoms
Pregnancy & Lactation
- Use during pregnancy if benefits justify risks
- Excretion into human milk unknown
- Advice for breastfeeding women
Precautions & Warnings
- Risk of suicidal thoughts and self-harm
- Caution in patients with cardiovascular disease
- Caution in patients with a history of seizures
- Consider dose reduction for tardive dyskinesia
- Discontinue in case of neuroleptic malignant syndrome
- Caution in patients with QT prolongation history
- Reporting of severe neutropenia
- Observation for hyperglycemia and diabetes mellitus
Use in Special Populations
- Caution in the elderly
- Different dosing in children and adolescents
Overdose Effects
- Survival in reported acute overdoses
- No specific antidote
- Consideration of multiple drug involvement
- Need for intensive care procedures
Therapeutic Class
- Atypical neuroleptic drugs
Storage Conditions
- Keep out of sight and reach of children
- Do not use after expiry date
- Store in a cool and dry place away from light