Egyl 400 mg (Tablet)
Unit Price: ৳ 1.70 (10 x 10: ৳ 170.00)
Strip Price: ৳ 17.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Metronidazole |
| Company | Euro pharma ltd |
| Also available as |
Title
- Egyl 400 mg Tablet
Categories
- Antibiotic
- Antiparasitic
- Antiprotozoal
- Amoebicide
Description
- Treatment of post-operative infections
- Treatment of septicaemia
- Treatment of trichomoniasis
- Treatment of bacterial vaginosis
- Treatment of amoebiasis
- Treatment of giardiasis
- Treatment of gingivitis
- Treatment of anaerobic infections
- Surgical prophylaxis
- Vaginal gel application
- Suppository application
- IV infusion
DosageInstructions
- 200-800 mg 2-3 times daily
- 1-2 gm once daily
- Intravaginal application once or twice daily for 5 days
- 1 g every 8-12 hours for 3 days
Pharmacology
- Imidazole class antibacterial drug
- Antiprotozoal agent
- Interacts with DNA for bactericidal action
Interaction
- Disulfiram - may cause psychotic reactions
- Alcohol - may lead to disulfiram-like reaction
- Warfarin - potentiation of anticoagulant effect
- Lithium - may increase plasma levels
- Cyclosporin - requires close monitoring
- Phenytoin or phenobarbital - may reduce plasma levels
- 5-Fluorouracil - may increase toxicity
- Busulfan - may increase plasma levels
Contraindications
- Hypersensitivity to Metronidazole or Nitroimidazole derivatives
SideEffects
- Metallic taste
- Nausea
- Vomiting
- Diarrhoea
- Drowsiness
- Rashes
PregnancyAndLactation
- FDA Pregnancy Category B
- Excreted in human milk
- Caution advised during pregnancy and lactation
PrecautionsAndWarnings
- Regular hematological tests recommended for longer duration use
- Caution in hepatic encephalopathy patients
- Darkening of urine may occur
SpecialPopulations
- Reduced dosage in hepatic impairment
- No dosage adjustment in renal impairment
- Efficient removal during hemodialysis
StorageConditions
- Store below 30°C
- Protect from light
- Keep out of reach of children
- Do not use post expiry
CommonQuestions
- Uses for viral and parasitic infections
- Side effects include diarrhoea, headache, weakness
- Improvement may be seen in 1-2 days
- Contraindications include hives, flushing, nasal congestion
- Not recommended in pregnancy unless necessary
- High doses can lead to increased side effects
OverdoseEffects
- Reported symptoms limited to vomiting, ataxia and disorientation
- No specific antidote
- Supportive treatment suggested for suspected overdosages
TherapeuticClass
- Amoebicides
- Anti-diarrhoeal
- Antiprotozoal
ModeOfAction
- Reduction by anaerobes metabolically
- DNA interaction leading to bactericidal action