Emlidus 25 mg+5 mg (Tablet)
Unit Price: ৳ 40.00 (1 x 14: ৳ 560.00)
Strip Price: ৳ 560.00
Medicine Details
Category | Details |
---|---|
Generic | Empagliflozin linagliptin |
Company | Opsonin pharma ltd |
Also available as |
Indications
- Adjunct to diet and exercise for type 2 diabetes mellitus
Pharmacology
- Inhibits DPP-4 enzyme
- Increases active incretin hormones
- Inhibitor of Sodium-glucose co-transporter 2 (SGLT2)
Dosage & Administration
- Recommended dose of 10 mg Empagliflozin and 5 mg Linagliptin once daily
- Increased dose to 25 mg Empagliflozin and 5 mg Linagliptin once daily
- Assess renal function before initiating
Interaction
- Coadministration with diuretics
- Coadministration with Insulin or Insulin Secretagogues
- Interaction with P-glycoprotein or CYP3A4 Enzymes
- Positive urine glucose test
- Interference with 1,5-anhydroglucitol (1,5-AG) Assay
Contraindications
- Severe renal impairment or end-stage renal disease
- Hypersensitivity reaction to Linagliptin or Empagliflozin
Side Effects
- Pancreatitis
- Ketoacidosis
- Volume Depletion
- Urosepsis and Pyelonephritis
- Hypoglycemia
- Necrotizing Fasciitis of the Perineum
- Genital Mycotic Infections
- Hypersensitivity Reactions
- Severe and Disabling Arthralgia
- Bullous Pemphigoid
- Heart Failure
Pregnancy & Lactation
- Not recommended during second and third trimesters
- Limited available data in pregnant women
Precautions & Warnings
- Pancreatitis
- Ketoacidosis
- Volume Depletion
- Urosepsis and Pyelonephritis
- Hypoglycemia with Concomitant Use with Insulin
- Necrotizing Fasciitis of the Perineum
- Genital Mycotic Infections
- Hypersensitivity Reactions
- Heart Failure
Overdose Effects
- Contact Poison Control Center
- Usual supportive measures
- Removal of Empagliflozin by hemodialysis not studied
- Removal of Linagliptin by hemodialysis unlikely
Therapeutic Class
- Sodium-glucose Cotransporter-2 (SGLT2) Inhibitors
Storage Conditions
- Store below 30°C
- Keep away from light and wet place
- Keep out of reach of children