Emlidus 25 mg+5 mg (Tablet)

Unit Price: ৳ 40.00 (1 x 14: ৳ 560.00)
Strip Price: ৳ 560.00

Medicine Details

Category Details
Generic Empagliflozin linagliptin
Company Opsonin pharma ltd
Also available as

Indications

  • Adjunct to diet and exercise for type 2 diabetes mellitus

Pharmacology

  • Inhibits DPP-4 enzyme
  • Increases active incretin hormones
  • Inhibitor of Sodium-glucose co-transporter 2 (SGLT2)

Dosage & Administration

  • Recommended dose of 10 mg Empagliflozin and 5 mg Linagliptin once daily
  • Increased dose to 25 mg Empagliflozin and 5 mg Linagliptin once daily
  • Assess renal function before initiating

Interaction

  • Coadministration with diuretics
  • Coadministration with Insulin or Insulin Secretagogues
  • Interaction with P-glycoprotein or CYP3A4 Enzymes
  • Positive urine glucose test
  • Interference with 1,5-anhydroglucitol (1,5-AG) Assay

Contraindications

  • Severe renal impairment or end-stage renal disease
  • Hypersensitivity reaction to Linagliptin or Empagliflozin

Side Effects

  • Pancreatitis
  • Ketoacidosis
  • Volume Depletion
  • Urosepsis and Pyelonephritis
  • Hypoglycemia
  • Necrotizing Fasciitis of the Perineum
  • Genital Mycotic Infections
  • Hypersensitivity Reactions
  • Severe and Disabling Arthralgia
  • Bullous Pemphigoid
  • Heart Failure

Pregnancy & Lactation

  • Not recommended during second and third trimesters
  • Limited available data in pregnant women

Precautions & Warnings

  • Pancreatitis
  • Ketoacidosis
  • Volume Depletion
  • Urosepsis and Pyelonephritis
  • Hypoglycemia with Concomitant Use with Insulin
  • Necrotizing Fasciitis of the Perineum
  • Genital Mycotic Infections
  • Hypersensitivity Reactions
  • Heart Failure

Overdose Effects

  • Contact Poison Control Center
  • Usual supportive measures
  • Removal of Empagliflozin by hemodialysis not studied
  • Removal of Linagliptin by hemodialysis unlikely

Therapeutic Class

  • Sodium-glucose Cotransporter-2 (SGLT2) Inhibitors

Storage Conditions

  • Store below 30°C
  • Keep away from light and wet place
  • Keep out of reach of children

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