Adlina-EM 25 mg+5 mg (Tablet)

Unit Price: ৳ 40.00 (1 x 10: ৳ 400.00)
Strip Price: ৳ 400.00

Medicine Details

Category Details
Generic Empagliflozin linagliptin
Company Unimed unihealth pharmaceuticals ltd
Also available as
Adlina em 10 mg tablet

Indications

  • Adjunct to diet and exercise
  • Improves glycemic control
  • Type 2 diabetes mellitus

Pharmacology

  • Inhibits DPP-4 enzyme
  • Increases active incretin hormones
  • Stimulates insulin release
  • Reduces glucagon levels
  • Inhibitor of Sodium-glucose co-transporter 2
  • Increases urinary glucose excretion

Dosage & Administration

  • Recommended dose: 10 mg Empagliflozin and 5 mg Linagliptin once daily
  • Increased dose: 25 mg Empagliflozin and 5 mg Linagliptin once daily
  • Renal impaired patients assessment

Interaction

  • Diuretics coadministration
  • Insulin or Insulin Secretagogues coadministration
  • Inducers of P-glycoprotein or CYP3A4 Enzymes
  • Positive Urine Glucose Test
  • Interference with 1,5-anhydroglucitol (1,5-AG) Assay

Contraindications

  • Severe renal impairment
  • Hypersensitivity reaction to Linagliptin
  • Hypersensitivity reaction to Empagliflozin

Side Effects

  • Pancreatitis
  • Ketoacidosis
  • Volume Depletion
  • Urosepsis and Pyelonephritis
  • Hypoglycemia with Concomitant Use with Insulin and Insulin Secretagogues
  • Necrotizing Fasciitis of the Perineum
  • Genital Mycotic Infections
  • Hypersensitivity Reactions
  • Severe and Disabling Arthralgia
  • Bullous Pemphigoid
  • Heart Failure

Pregnancy & Lactation

  • Not recommended during second and third trimesters
  • Limited available data
  • Risks to mother and fetus

Precautions & Warnings

  • Pancreatitis
  • Hypotension
  • Ketoacidosis
  • Acute kidney injury
  • Urosepsis and Pyelonephritis
  • Genital Mycotic Infections
  • Hypersensitivity
  • Necrotizing Fasciitis of the Perineum
  • Heart Failure

Overdose Effects

  • Contact Poison Control Center
  • Supportive measures
  • Hemodialysis study

Therapeutic Class

  • Sodium-glucose Cotransporter-2 (SGLT2) Inhibitors

Storage Conditions

  • Store below 30°C
  • Keep away from light and wet place
  • Keep out of reach of children

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