Rostab 10 mg (Tablet)

Unit Price: ৳ 26.00 (3 x 10: ৳ 780.00)
Strip Price: ৳ 260.00

Medicine Details

Category Details
Generic Rosuvastatin calcium
Company Acme laboratories ltd
Also available as
Rostab 20 mg tablet Rostab 5 mg tablet

Indications

  • Heterozygous Hypercholesterolemia (Familial and Non familial)
  • Homozygous Hypercholesterolemia (Familial)
  • Mixed Dyslipidemia (Fredrickson Type IIa and IIb)
  • Primary prevention of cardiovascular disease

Pharmacology

  • Mechanism of Action: Inhibitor of HMG-CoA reductase
  • Lipid-modifying Effects:
    • Increases hepatic LDL receptors for enhanced uptake and catabolism of LDL
    • Inhibits hepatic synthesis of VLDL, reducing total number of VLDL and LDL particles

Dosage

  • Dose Range: 5-40 mg once daily
  • HoFH Starting Dose: 20 mg/day
  • Pediatric Patients with HeFH:
    • 5-10 mg/day for patients 8 to less than 10 years age
    • 5-20 mg/day for patients 10 to 17 years of age
  • Pediatric Patients with HoFH: 20 mg/day for patients 7 to 17 years of age

Administration

Can be taken with or without food, at any time of day

Drug Interactions

  • Cyclosporine
  • Gemfibrosil
  • Lopinavir/Ritonavir or atazanavir/ritonavir
  • Coumarin anticoagulants
  • Concomitant lipid-lowering therapies

Contraindications

  • Known hypersensitivity to product components
  • Liver disease, including unexplained persistent elevations in hepatic transaminase levels
  • Pregnant women and women who may become pregnant
  • Nursing mothers

Side Effects

  • Headache
  • Myalgia
  • Constipation
  • Asthenia
  • Abdominal pain
  • Nausea

Pregnancy & Lactation

  • Safety in Pregnant Women: Not established
  • Excretion in Human Milk: Unknown

Precautions & Warnings

  • Skeletal Muscle Effects: Risks increase with use of 40 mg dose, advanced age, hypothyroidism, renal impairment, and certain other lipid-lowering drugs
  • Prompt Reporting: Patients should report unexplained muscle pain, tenderness or weakness
  • Liver Enzyme Abnormalities: Persistent elevations in hepatic transaminases can occur. Liver enzymes should be monitored before and during treatment

Use in Special Populations

Safety and effectiveness in pediatric patients have not been established

Therapeutic Class

Other Anti-anginal & Anti-ischaemic drugs, Statins

Storage Conditions

Keep below 30°C temperature, protected from light and moisture. Keep out of the reach of children

Chemical Structure

  • Molecular Formula: C22H28FN3O6S

Common Questions about Rostab 10 mg Tablet

  • What is Rostab 10 mg Tablet?: A HMG-CoA reductase inhibitor helpful in lowering cholesterol level and triglycerides
  • Uses:
    • Hyperlipidemia
    • Hypertriglyceridemia
    • Type 3 Hyperlipoproteinemia
    • Stroke
  • Side Effects:
    • Muscle pain
    • Weakness
    • Headache
    • Abdominal pain
  • Duration of Use: Until improvement in medical condition, as per doctor’s instructions
  • Weight Gain Potential: Very rare side effect, not typically associated with the medication
  • Tiredness: Common side effect, but exact reason behind it is unknown
  • Best Time to Take: Not mandatory to take at night, can be taken in the morning, once a day
  • Foods to Avoid: Junk food and high-calorie foods that can increase cholesterol levels
  • Beneficial Effects: Improvement in medical condition indicates its effectiveness
  • Memory Loss Potential: Very unusual side effect, consult doctor if experienced
  • Diabetes Risk: Does not cause diabetes, but may increase risk in those already at higher risk
  • Alcohol Consumption: Should be avoided as it can increase the risk of liver problems and triglyceride levels
  • Muscle Problems or Injury: Muscle pain is the most common side effect, consult doctor if discomfort persists

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