Midazolam Hameln 50 mg/50 ml (IM/IV Injection)
Medicine Details
Category | Details |
---|---|
Generic | Midazolam |
Company | Siegfried hameln germany |
Product Title
- Midazolam Hameln Hameln
Categories
- Medicine
- Sleep Aid
- Anxiolytic
- Sedative
- Benzodiazepine
Description
A sleep-inducing agent with rapid onset and short duration of action. It exerts anxiolytic, anticonvulsant, and muscle-relaxant effects.
Indications
- Short-term treatment of insomnia
- Sedation in premedication before surgical or diagnostic procedures
Pharmacology
Mediated through the inhibitory neurotransmitter gamma-aminobutyric acid (GABA), resulting in sedating effect, muscle relaxation, and induction of sleep, anesthesia, and amnesia
Dosage & Administration
- Oral, Intravenous, Intramuscular, Rectal administration for adults, elderly, debilitated patients, and children
Interaction
Can enhance the central sedative effect of neuroleptics, tranquillizers, antidepressants, analgesics, anaesthetics, antipsychotics, antiepileptic drugs, sedative antihistamines
Contraindications
- Severe respiratory insufficiency
- Severe hepatic insufficiency
- Myasthenia gravis
- Sleep apnea syndrome
- Known hypersensitivity to benzodiazepines or any component of the product
Side Effects
- Drowsiness, confusion, fatigue, headache, muscle weakness, respiratory depression, apnea, variations in blood pressure, pulse rate
Pregnancy & Lactation
Should be avoided during pregnancy and not administered to breastfeeding mothers
Precautions & Warnings
IV administration should be very slow
Overdose Effects
May lead to coma, areflexia, cardiorespiratory depression, apnea. Can be controlled with benzodiazepine antagonist flumazenil
Therapeutic Class
- Benzodiazepine hypnotics
- Benzodiazepine sedatives
Storage Conditions
Protect from light and moisture, store in a cool and dry place. Keep out of the reach of children.