Docetaxel PhaRes 80 mg/vial (IV Infusion)
80 mg vial: ৳ 11,730.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Docetaxel trihydrate |
| Company | Thymoorgan pharmazie gmbh germany |
| Also available as |
Indications
- Breast Cancer single-agent treatment
- Breast Cancer adjuvant treatment
- Non-small Cell Lung Cancer single-agent treatment
- Non-small Cell Lung Cancer chemotherapy-naive treatment
- Castration-Resistant Prostate Cancer treatment
- Gastric Adenocarcinoma treatment
- Squamous Cell Carcinoma of the Head and Neck treatment
Pharmacology
- Antineoplastic agent
- Disrupts microtubular network
- Promotes assembly of tubulin into stable microtubules
- Inhibits microtubule disassembly
Dosage & Administration
- Administered intravenously
- Administered over 1 hr every 3 weeks
- Specific dosages for different indications
- Premedication with oral corticosteroids
- Adjustable dose
Interaction
- CYP3A4 substrate
- Metabolism modification potential
Contraindications
- Neutrophil counts < 1500 cells/mm3
- Severe hypersensitivity reactions to docetaxel
Side Effects
- Infections
- Neutropenia
- Anemia
- Febrile neutropenia
- Hypersensitivity
- Thrombocytopenia
- Neuropathy
- Dysgeusia
- Dyspnea
- Constipation
- Anorexia
- Nail disorders
- Fluid retention
- Asthenia
- Pain
- Nausea
- Diarrhea
- Vomiting
- Mucositis
- Alopecia
- Skin reactions
- Myalgia
Pregnancy & Lactation
- Potential fetal harm
- No information on presence in human milk
Precautions & Warnings
- Physician supervision required
- Higher risk in patients with hepatic impairment
- Neutrophil count guideline
- Fatal gastrointestinal complications possible
- Severe hypersensitivity reactions may occur
- Risk of treatment-related acute myeloid leukemia
Overdose Effects
- No known antidote
- Complications may include bone marrow suppression, peripheral neurotoxicity, and mucositis
- Close monitoring and symptomatic measures required
Therapeutic Class
- Cytotoxic Chemotherapy
Storage Conditions
- Store between 2°C and 25°C
- Protected from light
- Freezing does not adversely affect the product