Docetaxel PhaRes 20 mg/vial (IV Infusion)

20 mg vial: ৳ 3,900.00

Medicine Details

Category	Details
Generic	Docetaxel trihydrate
Company	Thymoorgan pharmazie gmbh germany
Also available as	Docetaxel phares 80 mg injection

Indications

Breast Cancer treatment as a single agent
Adjuvant treatment for operable node-positive Breast Cancer
Non-small Cell Lung Cancer treatment
Castration-Resistant Prostate Cancer treatment
Gastric Adenocarcinoma treatment
Squamous Cell Carcinoma of the Head and Neck treatment

Pharmacology

Acts by disrupting the microtubular network
Promotes the assembly of tubulin into stable microtubules
Inhibits the disassembly of microtubules

Dosage & Administration

Administer intravenously over 1 hr every 3 weeks
Dosage varies based on cancer type and treatment stage
PVC equipment not recommended

Interaction

CYP3A4 substrate
Metabolism may be modified by concomitant administration of certain compounds

Contraindications

Contraindicated in patients with neutrophil counts of <1500 cells/mm³
History of severe hypersensitivity reactions to docetaxel or polysorbate 80

Side Effects

Common adverse reactions include infections, neutropenia, anemia, hypersensitivity
Adverse reaction incidence varies by indication

Pregnancy & Lactation

Can cause fetal harm when administered to a pregnant woman
No information on presence in human milk or effects on breastfeeding

Precautions & Warnings

Higher risk of severe adverse reactions in patients with hepatic impairment
Close monitoring required for severe hypersensitivity reactions
Administered under the supervision of a physician experienced in antineoplastic agents

Overdose Effects

No known antidote for docetaxel overdose
Bone marrow suppression, peripheral neurotoxicity, and mucositis are anticipated complications

Therapeutic Class

Cytotoxic Chemotherapy

Storage Conditions

Store between 2°C and 25°C
Protected from light
Freezing does not adversely affect the product

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