Rostab 20 mg (Tablet)
Unit Price: ৳ 30.00 (1 x 10: ৳ 300.00)
Strip Price: ৳ 300.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Rosuvastatin calcium |
| Company | Acme laboratories ltd |
| Also available as |
Indications
- Heterozygous Hypercholesterolemia (Familial and Non familial)
- Homozygous Hypercholesterolemia (Familial)
- Mixed Dyslipidemia (Fredrickson Type IIa and IIb)
- Primary prevention of cardiovascular disease
Pharmacology
- Selective and competitive inhibitor of HMG-CoA reductase
- Increases the number of hepatic LDL receptors
- Inhibits hepatic synthesis of VLDL
Dosage
- Dose range: 5-40 mg once daily
- Starting dose of 20 mg/day for HoFH
- Pediatric dose: 5-10 mg/day for patients 8 to less than 10 years age, 5-20 mg/day for patients 10 to 17 years of age
- Pediatric patients with HoFH: 20 mg/day for patients 7 to 17 years of age
Administration
- Can be taken with or without food
- At any time of day
Interaction
- Cyclosporine: Combination increases Rostab exposure
- Gemfibrosil: Combination should be avoided
- Lopinavir/Ritonavir or atazanavir/ritonavir: Combination increases Rostab exposure
- Coumarin anticoagulants: Combination prolongs international normalized ratio (INR)
- Concomitant lipid-lowering therapies: Use with fibrates and niacin products may increase the risk of skeletal muscle effects
Contraindications
- Known hypersensitivity to product components
- Liver disease, including unexplained persistent elevations in hepatic transaminase levels
- Pregnant women and women who may become pregnant
- Nursing mothers
Side Effects
- Headache
- Myalgia
- Constipation
- Asthenia
- Abdominal pain
- Nausea
Pregnancy & Lactation
- Safety in pregnant women has not been established
- Excretion in human milk not known
Precautions & Warnings
- Skeletal muscle effects: Risks increase with use of 40 mg dose, advanced age, hypothyroidism, renal impairment
- Liver enzyme abnormalities and monitoring: Persistent elevations in hepatic transaminases can occur
Use in Special Populations
- Safety and effectiveness in pediatric patients have not been established
Therapeutic Class
- Other Anti-anginal & Anti-ischaemic drugs
- Statins
Storage Conditions
- Keep below 30°C temperature
- Protected from light & moisture
- Keep out of the reach of children
Chemical Structure
- Molecular Formula: C22H28FN3O6S
- Chemical Structure: Refer to image link
Common Questions about Rostab 20 mg Tablet
- Rostab 20 mg Tablet is a HMG-CoA reductase inhibitor drug which is helpful in lowering the cholesterol level and triglycerides in the body
- Useful against the conditions like Hyperlipidemia, Hypertriglyceridemia, Type 3 Hyperlipoproteinemia and Stroke
- Side effects include Muscle pain, Weakness, Headache and Abdominal pain
- Duration of use should be as per doctor's instructions
- Weight gain is a very rare side effect
- Tiredness and fatigue is a common side effect
- Not mandatory to take at night
- Avoid eating junk food and high calorie foods
- Beneficial if improvement in condition is noticed
- Memory loss is a very unusual side effect
- Does not cause diabetes but can increase the risk factor for those already at higher risk
- Alcohol should not be taken during the course of treatment
- Muscle problems are common, consult doctor if discomfort