Megexia 160 mg (Tablet)
Unit Price: ৳ 88.00 (3 x 10: ৳ 2,640.00)
Strip Price: ৳ 880.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Megestrol acetate |
| Company | Doppel farmaceutici srl italy |
Indications
- Palliative treatment of advanced carcinoma of the breast or endometrium
- Treatment of anorexia, cachexia, or unexplained weight loss in AIDS & cancer patients
Pharmacology
- Synthetic, antineoplastic and progestational drug
- Inhibition of pituitary gonadotrophin production
- Decrease in estrogen secretion
- Modification of action of other steroid hormones
- Direct cytotoxic effect on tumor cells
- Estimates of plasma levels
- Peak plasma concentrations after oral dose
- Plasma half-life
- Excretion in urine and feces
Dosage & Administration
- Tablet dosage for breast cancer and endometrial carcinoma
- Duration of continuous treatment for efficacy assessment
- Oral suspension dosage for adults
Interaction
- Lack of investigation on interactions with concomitant medications
- Potential fluid retention with estrogens and progestogens therapy
Contraindications
- Hypersensitivity to Megestrol Acetate or any component
- Known or suspected pregnancy
Side Effects
- Weight gain
- Thromboembolic phenomena
- Glucocorticoid effects
- Nausea
- Dyspnea
- Tumor flare
- Hyperglycemia
- Glucose intolerance
- Alopecia
- Hypertension
- Carpal tunnel syndrome
- Mood changes
- Hot flashes
- Malaise
- Asthenia
- Lethargy
- Sweating
- Rash
Pregnancy & Lactation
- Pregnancy Category D
- Excretion in mother's milk
- Potential harmful effects on newborn
- Discontinuation of nursing during treatment
Precautions & Warnings
- Close surveillance for patients with recurrent or metastatic cancer
- Caution in patients with history of thromboembolic disease
- Exacerbation of preexisting diabetes
Use in Special Populations
- Lack of established safety and effectiveness in pediatric patients
- Insufficient data for patients 65 years and older
Overdose Effects
- No serious unexpected side effects at high dosages
Storage Conditions
- Storage in cool, dry place below 30°C
- Protection from light and moisture
- Keep out of reach of children