AlbuRx 25% (IV Infusion)

Indications

• Emergency treatment of shock
• Treatment of burns
• Treatment of hypoproteinemia with or without edema

Pharmacology

• Contribution to plasma colloid oncotic pressure
• Transport function for hormones, enzymes, medicines, and toxins
• Antioxidant properties
• Capillary membrane integrity maintenance

Dosage & Administration

• For intravenous administration only
• May be diluted with 5% glucose or 0.9% sodium chloride
• Adjust concentration, dosage, and infusion-rate to individual requirements
• Monitoring haemodynamic performance
• Administered directly or diluted in an isotonic solution

Interaction

• Should not be mixed by protein hydrolysates or alcoholic solutions
• Increased risk of atypical reactions to ACE inhibitors in patients undergoing therapeutic plasma exchange with albumin human replacement

Contraindications

• Severe anemia or cardiac failure
• History of allergic reactions to human albumin

Side Effects

• Allergic or pyrogenic reactions
• Fever and chills
• Rash, nausea, vomiting
• Tachycardia and hypotension
• Vascular overload with resultant pulmonary edema

Pregnancy & Lactation

• Pregnancy Category C
• Potential risk to the fetus

Precautions & Warnings

• Hypertension or low cardiac reserve
• Monitor for signs of cardiac overload
• May carry risk of viral transmission
• Individualized volume admin and rate of infusion
• Concerns for use during pregnancy and lactation

Use in Special Populations

• No clinical studies in pediatric patients
• Safety and effectiveness not established in pediatric patients
• Children respond similarly to adults

Therapeutic Class

• Plasma expanders

Storage Conditions

• Store below 30°C
• Do not freeze

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