Telmivas 80 mg (Tablet)
Unit Price: ৳ 20.00 (3 x 10: ৳ 600.00)
Strip Price: ৳ 200.00
Medicine Details
Category | Details |
---|---|
Generic | Telmisartan |
Company | Popular pharmaceuticals ltd |
Also available as |
Indications
- Treatment of essential hypertension in adults
- Reduction of cardiovascular morbidity in individuals with atherothrombotic cardiovascular disease or type 2 diabetes mellitus with documented target organ damage
Pharmacology
- Non-peptide angiotensin-II receptor antagonist
- Blocks vasoconstrictor and aldosterone-secreting effects of angiotensin-II
- Selective blocking of the binding of angiotensin-II to the AT1 receptor
- Greater affinity for the AT1 receptor than for the AT2 receptor
- Independence from pathways for angiotensin-II synthesis
Dosage & Administration
- Usual starting dose of 40 mg once a day
- Dose-related blood pressure response in the range of 20 to 80 mg
- Most antihypertensive effect apparent within 2 weeks
- Maximal reduction generally attained after 4 weeks
- No initial dosage adjustment necessary for elderly patients or those with renal impairment
- May be administered with other antihypertensive agents
- May be administered with or without food
- Not recommended for patients ≥75 years old or with hepatic impairment
- Monitoring and slow titration in patients with biliary obstructive disorders or hepatic insufficiency
Interaction
- Increased risk of renal impairment and loss of antihypertensive effect with NSAIDs
- Avoid co-administration with aliskiren in patients with diabetes
Contraindications
- Known hypersensitivity to the product or any of its components
Side Effects
- Common side effects in hypertensive patients: sinus pain, congestion, back pain, diarrhea
- Common side effects in patients of cardiovascular risk reduction: intermittent claudication, skin ulcer
Pregnancy & Lactation
- Pregnancy Category C (first trimester) and D (second and third trimester)
- Potential for adverse effects on the nursing infant
- Consideration of discontinuation of nursing or the drug, accounting for the drug's importance to the mother
Precautions & Warnings
- Avoid fetal or neonatal exposure
- Hypotension
- Monitoring in patients with impaired hepatic or renal function
- Avoid concomitant use of an ACE inhibitor and angiotensin receptor blocker
Overdose Effects
- Hypotension
- Dizziness
- Tachycardia
- Bradycardia
- Increase in serum creatinine
- Acute renal failure
Therapeutic Class
- Angiotensin-II receptor blocker
Storage Conditions
- Do not store above 30°C
- Protect from light and high humidity
- Keep out of the reach of children