Rostatin 5 mg (Tablet)
Unit Price: ৳ 8.00 (3 x 14: ৳ 336.00)
Strip Price: ৳ 112.00
Medicine Details
Category | Details |
---|---|
Generic | Rosuvastatin calcium |
Company | Drug international ltd |
Also available as |
Indications
- Heterozygous Hypercholesterolemia (Familial and Non familial)
- Homozygous Hypercholesterolemia (Familial)
- Mixed Dyslipidemia (Fredrickson Type IIa and IIb)
- Primary prevention of cardiovascular disease
Pharmacology
Selective and competitive inhibitor of HMG-CoA reductase, enhances uptake and catabolism of LDL, inhibits hepatic synthesis of VLDL
Dosage
- Dose range: 5-40 mg once daily
- HoFH starting dose 20 mg/day
- Pediatric patients with HeFH: 5-10 mg/day for patients 8 to less than 10 years age
- Pediatric patients with HoFH: 20 mg/day for patients 7 to 17 years of age
Administration
Can be taken with or without food, at any time of day
Interaction
- Cyclosporine increases exposure. Dose limited to 5 mg once daily
- Gemfibrosil combination should be avoided or limited to 10 mg once daily
- Lopinavir/Ritonavir or atazanavir/ritonavir increases exposure. Dose limited to 10 mg once daily
- Coumarin anticoagulants prolong INR, to be monitored frequently
- Use with fibrates and niacin products may increase risk of skeletal muscle effects
Contraindications
- Known hypersensitivity to product components
- Liver disease, unexplained persistent elevations in hepatic transaminase levels
- Pregnant women and women who may become pregnant
- Nursing mothers
Side Effects
- Headache
- Myalgia
- Constipation
- Asthenia
- Abdominal pain
- Nausea
Pregnancy & Lactation
Safety not established in pregnant women, excretion in human milk unknown
Precautions & Warnings
- Skeletal muscle effects increase with 40 mg dose, advanced age, hypothyroidism, renal impairment, and certain lipid-lowering drugs use
- Liver enzyme abnormalities and monitoring recommended
Use in Special Populations
Safety and effectiveness in pediatric patients not established
Therapeutic Class
- Other Anti-anginal & Anti-ischaemic drugs
- Statins
Storage Conditions
Keep below 30°C temperature, protected from light & moisture, keep out of the reach of children
Chemical Structure
- Molecular Formula: C22H28FN3O6S
- Chemical Structure Image: https://medex.com.bd/storage/res/g-res-970-rosuvastatin-calcium-chemical-structure-UjXgzBvpDHiLnIP3gZua.svg
Common Questions
- What is Rostatin 5 mg Tablet?
- What are the uses of Rostatin 5 mg Tablet?
- What are the side effects of Rostatin 5 mg Tablet?
- For how long should I take Rostatin 5 mg Tablet?
- Does Rostatin 5 mg Tablet cause weight gain?
- Does Rostatin 5 mg Tablet make you tired?
- Should Rostatin 5 mg Tablet be taken at night?
- What foods should be avoided when taking Rostatin 5 mg Tablet?
- How do I know whether Rostatin 5 mg Tablet is beneficial for me or not?
- Can Rostatin 5 mg Tablet cause memory loss?
- Is it true that Rostatin 5 mg Tablet can cause diabetes?
- Can I take alcohol with Rostatin 5 mg Tablet?
- Can Rostatin 5 mg Tablet cause muscle problems or muscle injury?
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