Rostatin 5 mg (Tablet)

Unit Price: ৳ 8.00 (3 x 14: ৳ 336.00)
Strip Price: ৳ 112.00

Medicine Details

Indications

  • Heterozygous Hypercholesterolemia (Familial and Non familial)
  • Homozygous Hypercholesterolemia (Familial)
  • Mixed Dyslipidemia (Fredrickson Type IIa and IIb)
  • Primary prevention of cardiovascular disease

Pharmacology

Selective and competitive inhibitor of HMG-CoA reductase, enhances uptake and catabolism of LDL, inhibits hepatic synthesis of VLDL

Dosage

  • Dose range: 5-40 mg once daily
  • HoFH starting dose 20 mg/day
  • Pediatric patients with HeFH: 5-10 mg/day for patients 8 to less than 10 years age
  • Pediatric patients with HoFH: 20 mg/day for patients 7 to 17 years of age

Administration

Can be taken with or without food, at any time of day

Interaction

  • Cyclosporine increases exposure. Dose limited to 5 mg once daily
  • Gemfibrosil combination should be avoided or limited to 10 mg once daily
  • Lopinavir/Ritonavir or atazanavir/ritonavir increases exposure. Dose limited to 10 mg once daily
  • Coumarin anticoagulants prolong INR, to be monitored frequently
  • Use with fibrates and niacin products may increase risk of skeletal muscle effects

Contraindications

  • Known hypersensitivity to product components
  • Liver disease, unexplained persistent elevations in hepatic transaminase levels
  • Pregnant women and women who may become pregnant
  • Nursing mothers

Side Effects

  • Headache
  • Myalgia
  • Constipation
  • Asthenia
  • Abdominal pain
  • Nausea

Pregnancy & Lactation

Safety not established in pregnant women, excretion in human milk unknown

Precautions & Warnings

  • Skeletal muscle effects increase with 40 mg dose, advanced age, hypothyroidism, renal impairment, and certain lipid-lowering drugs use
  • Liver enzyme abnormalities and monitoring recommended

Use in Special Populations

Safety and effectiveness in pediatric patients not established

Therapeutic Class

  • Other Anti-anginal & Anti-ischaemic drugs
  • Statins

Storage Conditions

Keep below 30°C temperature, protected from light & moisture, keep out of the reach of children

Chemical Structure

  • Molecular Formula: C22H28FN3O6S
  • Chemical Structure Image: https://medex.com.bd/storage/res/g-res-970-rosuvastatin-calcium-chemical-structure-UjXgzBvpDHiLnIP3gZua.svg

Common Questions

  • What is Rostatin 5 mg Tablet?
  • What are the uses of Rostatin 5 mg Tablet?
  • What are the side effects of Rostatin 5 mg Tablet?
  • For how long should I take Rostatin 5 mg Tablet?
  • Does Rostatin 5 mg Tablet cause weight gain?
  • Does Rostatin 5 mg Tablet make you tired?
  • Should Rostatin 5 mg Tablet be taken at night?
  • What foods should be avoided when taking Rostatin 5 mg Tablet?
  • How do I know whether Rostatin 5 mg Tablet is beneficial for me or not?
  • Can Rostatin 5 mg Tablet cause memory loss?
  • Is it true that Rostatin 5 mg Tablet can cause diabetes?
  • Can I take alcohol with Rostatin 5 mg Tablet?
  • Can Rostatin 5 mg Tablet cause muscle problems or muscle injury?
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