Sporagin 50 mg/5 ml (Oral Solution)
100 ml bottle: ৳ 400.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Itraconazole |
| Company | Ibn sina pharmaceuticals ltd |
| Also available as |
Indications
- Treatment of oropharyngeal candidiasis
- Treatment of vulvovaginal candidiasis
- Treatment of pityriasis versicolor
- Treatment of tinea pedis
- Treatment of tinea cruris
- Treatment of tinea corporis
- Treatment of tinea manuum
- Treatment of onychomycosis
- Treatment of histoplasmosis
- Treatment of systemic candidiasis
- Treatment of aspergillosis
- Treatment of cryptococcosis
- Maintenance therapy in AIDS patients
- Prevention of fungal infection during prolonged neutropenia
Pharmacology
- Inhibition of Cytochrome P-450 dependent enzymes
- Impairment of ergosterol biosynthesis
- Abnormalities in permeability
- Abnormal cell wall formation
- Accumulation of intracellular lipids
- Utilizes SUBA (Super Bio-available) technology for enhanced bioavailability
- Demonstrated broad spectrum of activity
- Favorable pharmacokinetic profile
Dosage & Administration
- 100 & 200 mg preparation
- 65 mg & 130 mg preparation
- Specific dosages for different fungal diseases
- Adjustable dosage based on clinical response
- Pediatric use unestablished
Interaction
- Contraindicated drugs: terfenadine, astemizole, cisapride, simvastatin, oral midazolam, triazolam
- Significant interactions with rifampin, phenytoin, phenobarbital, digoxin, calcium channel blockers
- No experience with overdosage
Contraindications
- Known hypersensitivity to the drug or any ingredient
- Severe hepatic disease
- Concurrent use with rifampin
Side Effects
- Nausea
- Abdominal pain
- Dyspepsia
- Constipation
- Headache
- Dizziness
- Raised liver enzymes
- Menstrual disorders
- Allergic reactions
- Hepatitis
- Cholestatic jaundice
- Peripheral neuropathy
- Stevens-Johnson syndrome
- Hypokalaemia
- Oedema
- Hair loss
Pregnancy & Lactation
- Contraindicated in pregnancy
- Not recommended during breastfeeding
Precautions & Warnings
- Impaired absorption with reduced gastric acidity
- Administration after a full meal
- Cases of hepatitis and jaundice reported with prolonged use
- Monitoring of liver function advised for continuous treatment
Therapeutic Class
- Drugs for subcutaneous and mycoses
Storage Conditions
- Store below 25°C
- Keep in a cool & dry place
- Keep away from light
- Keep out of the reach of children
Common Questions about Sporagin 50 mg/5 ml Oral Solution
- Antifungal medication that inhibits Cytochrome P-450 dependent enzymes
- Used to treat fungal infections
- Duration of effect: 16 to 28 hours
- Onset of action: 2 hours
- Not recommended in pregnancy and breastfeeding
- Not habit-forming
- Quick tips for usage