Dexochol 300 mg (Tablet)

Unit Price: ৳ 36.00 (2 x 10: ৳ 720.00)

Strip Price: ৳ 360.00

Medicine Details

Category	Details
Generic	Ursodeoxycholic acid
Company	Radiant pharmaceuticals ltd
Also available as	Dexochol 150 mg tablet

Reduces cholesterol saturation of bile and promotes dissolution of gallstones.

Activity: Decreases secretion of cholesterol in bile
Mechanisms:
- Reduces cholesterol absorption
- Suppresses liver cholesterol synthesis
- Does not inhibit bile acid synthesis
Effects on Liver Diseases:
- Protects cholangiocytes against cytotoxicity of hydrophobic bile acids
- Stimulates hepatobilliary secretion
- Protects hepatocytes against bile acid-induced apoptosis
Absorption:
- Absorption Rate: 60-80%
- Time to Peak Serum Concentration: 30-150 minutes

Dissolution of Gall Stones: 8-12 mg/kg/day as single night time dose or in divided doses
Primary Billiary Cirrhosis: 10-15 mg/kg/day in 2-4 divided doses
Acute Viral Hepatitis: 600 mg/day
Alcoholic Fatty Liver: 300 mg/day
Primary Sclerosing Cholangitis: 25-30 mg/kg/day
Dissolution of Gallstones and Non-Alcoholic Steato Hepatitis: 13-15 mg/kg/day

Should not be used with drugs that increase bile cholesterol. Concomitant administration with bile-acid binding drugs should be avoided.

Category: B
Safety: No evidence of harm reported in pregnancy. Effectively used for treatment of cholestasis of pregnancy.
Breastfeeding: No documented problems

Should be used cautiously in those with liver disease.

Anti-gallstones drugs: Bile Acids

Store below 25°C, protected from light and moisture. Keep out of reach of children