Noradrenaline Aguettant 4 mg/4 ml (IV Infusion)
4 ml ampoule: ৳ 550.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Norepinephrine bitartrate |
| Company | Laboratoire aguettant france |
Indications
- blood pressure control
- acute hypotensive states
- pheochromocytomectomy
- sympathectomy
- poliomyelitis
- spinal anesthesia
- myocardial infarction
- septicemia
- blood transfusion
- drug reactions
- treatment of cardiac arrest
- profound hypotension
Pharmacology
- direct-acting sympathomimetic
- stimulates beta1 and alpha-adrenergic receptors
- vasoconstriction
- raises systolic and diastolic BP
- reflex slowing of heart rate
Dosage & Administration
- infusion into a large vein
- blood volume depletion correction
- dilution in 5 percent dextrose injection
- administration with blood volume replacement
- average dosage calculation
- high dosage titration
- fluid intake considerations
- duration of therapy
- adjunctive treatment in cardiac arrest
Interaction
- sensitization to anesthetics
- contraindicated with certain anesthetics
- caution with monoamine oxidase inhibitors and antidepressants
Contraindications
- hypotensive patients with blood volume deficits
- mesenteric or peripheral vascular thrombosis
- use during certain anesthesia
- profound hypoxia or hypercarbia
Side Effects
- ischemic injury
- bradycardia
- arrhythmias
- anxiety
- headache
- respiratory difficulty
- extravasation necrosis
- plasma volume depletion
- gangrene
- severe hypertension
Pregnancy & Lactation
- Pregnancy Category C
- unknown excretion in human milk
- caution during nursing
Precautions & Warnings
- avoiding hypertension
- site of infusion considerations
- extravasation precautions
- antidote for extravasation ischemia
Use in Special Populations
- safety and effectiveness in pediatric patients not established
- cautious use in elderly patients
- no carcinogenesis, mutagenesis, impairment of fertility studies
Overdose Effects
- headache
- severe hypertension
- reflex bradycardia
- marked increase in peripheral resistance
- decreased cardiac output
Therapeutic Class
- alpha and beta-adrenergic agonist
Reconstitution
- intravenous administration
- dilution with 5% glucose injection
- dilution with sodium chloride injection not recommended
Storage Conditions
- temperature not exceeding 30°C
- dry place
- protect from light