Vermikil 200 mg/5 ml (Oral Suspension)
10 ml bottle: ৳ 15.11
Medicine Details
| Category | Details |
|---|---|
| Generic | Albendazole |
| Company | Nipro jmi pharma ltd |
| Also available as |
Indications
- Treatment of single and mixed infestations of hookworm, roundworm, threadworm, whipworm, strongyloides, tapeworm, opisthorchi, and hydatid
Description
- Benzimidazole anthelmintic
- Active against nematodes and some cestodes
- Vermicidal, ovicidal, and larvicidal activity
- Inhibitory effect on tubulin polymerization
Pharmacology
- Broad spectrum anthelmintic
- Exhibits vermicidal, ovicidal, and larvicidal activities
- Blocks glucose uptake in susceptible helminths
- Exerts anthelmintic effect by binding and inhibiting parasite tubulin polymerization
Dosage & Administration
- 400 mg single dose for various infestations in adults and children over 2 years
- 200 mg single dose for children of 1-2 years
- Adult dosage for hydatid disease: 400 mg twice daily for patients over 60 kg
- Child dosage for hydatid disease: 15 mg/kg body weight daily, to a maximum total daily dose of 800 mg
- 400 mg once daily for five days in giardiasis
Interaction
- No reported pharmacodynamic or pharmacokinetic interactions
Contraindications
- Not recommended for neonates
- Reduced dose for children under 10 kg
- Avoid use in pregnant women
- No evidence for dosage alteration in renal, hepatic, or cardiac failure
Side Effects
- Gastrointestinal disturbances
- Headache
- Dizziness
- Changes in liver enzymes
- Rarely reversible alopecia
- Rash
- Fever
- Blood disorders including leucopenia and pancytopenia
- Allergic shock if cyst leakage
- Convulsions and meningism in cerebral disease
Pregnancy & Lactation
- Category C drug according to US FDA
- Avoid in pregnancy and lactation unless benefits outweigh risks
Precautions & Warnings
- Blood counts and liver function tests before treatment and during each cycle
- Exclude pregnancy before starting treatment
- Use with constant medical supervision for echinococcosis treatment
Therapeutic Class
- Anthelmintic
Storage Conditions
- Keep in a dry place
- Away from light and heat
- Keep out of the reach of children