Rosu 5 mg (Tablet)
Unit Price: ৳ 12.50 (5 x 10: ৳ 625.00)
Strip Price: ৳ 125.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Rosuvastatin calcium |
| Company | Popular pharmaceuticals ltd |
| Also available as |
Indications
- Heterozygous Hypercholesterolemia (Familial and Non familial)
- Homozygous Hypercholesterolemia (Familial)
- Mixed Dyslipidemia (Fredrickson Type IIa and IIb)
- Primary prevention of cardiovascular disease
Pharmacology
- Selective and competitive inhibitor of HMG-CoA reductase
- Increases hepatic LDL receptors
- Inhibits hepatic synthesis of VLDL
Dosage
- Dose range: 5-40 mg once daily
- Starting dose for HoFH: 20 mg/day
- Pediatric patients with HeFH: 5-20 mg/day
- Pediatric patients with HoFH: 20 mg/day
Administration
Can be taken with or without food, at any time of day
Interaction
- Cyclosporine: Limit Rosu dose to 5 mg once daily
- Gemfibrosil: Avoid combination or limit Rosu dose to 10 mg once daily
- Lopinavir/Ritonavir or atazanavir/ritonavir: Limit Rosu dose to 10 mg once daily
- Coumarin anticoagulants: Prolongs INR, monitor frequently
- Concomitant lipid-lowering therapies: Risk of skeletal muscle effects
Contraindications
- Known hypersensitivity to product components
- Liver disease
- Pregnant women and women who may become pregnant
- Nursing mothers
Side Effects
- Headache
- Myalgia
- Constipation
- Asthenia
- Abdominal pain
- Nausea
Pregnancy & Lactation
Safety not established in pregnant women, excretion in human milk unknown
Precautions & Warnings
- Skeletal muscle effects risk factors
- Liver enzyme abnormalities and monitoring
- Use in children safety and effectiveness not established
Therapeutic Class
- Other Anti-anginal & Anti-ischaemic drugs
- Statins
Storage Conditions
Keep below 30°C, protected from light & moisture, keep out of reach of children
Chemical Structure
- Molecular Formula: C22H28FN3O6S
- Chemical Structure Image: https://medex.com.bd/storage/res/g-res-970-rosuvastatin-calcium-chemical-structure-UjXgzBvpDHiLnIP3gZua.svg
Common Questions about Rosu 5 mg Tablet
- Uses to lower cholesterol level and triglycerides
- Useful against Hyperlipidemia, Hypertriglyceridemia, Type 3 Hyperlipoproteinemia and Stroke
- Side effects include Muscle pain, Weakness, Headache, and Abdominal pain
- Duration should be as per doctor’s instructions
- Does not cause weight gain
- Fatigue is a common side effect, consult a doctor if it persists
- Can be taken at any time of the day, ideally once a day
- Avoid high-calorie and junk food
- Beneficial if condition improves, consult a doctor if adverse side effects occur
- Can cause muscle problems, consult a doctor if discomfort persists
- Rosu 5 mg Tablet treats high cholesterol by lowering 'bad' cholesterol (LDL) and triglycerides
- In general, it is safe but may cause diarrhea, gas, or an upset stomach. If any of these happen, take it with food
- Inform doctor about fatigue, muscle weakness, or muscle pain
- Doctor may check liver function before and during treatment, consult if signs of liver problems appear
- Inform doctor about kidney disease, liver disease, or diabetes before treatment, monitor blood sugar level regularly, avoid if pregnant or breastfeeding