ABZ 400 mg (Chewable Tablet)
Unit Price: ৳ 4.00 (5 x 10: ৳ 200.00)
Strip Price: ৳ 40.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Albendazole |
| Company | Al madina pharmaceuticals ltd |
Indications
- Hookworm infestation
- Roundworm infestation
- Threadworm infestation
- Whipworm infestation
- Strongyloides infestation
- Tapeworm infestation
- Opisthorchi infestation
- Hydatid disease
Description
- Benzimidazole anthelmintic
- Active against most nematodes and some cestodes
- Vermicidal, ovicidal, and larvicidal activity
- Inhibitory effect on tubulin polymerization
Pharmacology
- Broad spectrum anthelmintic
- Blocks glucose uptake in susceptible helminths
- Depletes energy level leading to immobilization
- Extensively metabolized, mainly in the liver
- Poorly absorbed from the gastrointestinal tract
Dosage & Administration
- 400 mg single dose for certain types of infestations
- 400 mg daily for 3 days in cases of strongyloidiasis or taeniasis
- 200 mg single dose for children of 1-2 years
- Not recommended for children under 1 year
- 400 mg twice daily for 28 days for hydatid disease
- 15 mg/kg body weight daily in two divided doses for patients weighing less than 60 kg
- 400 mg once daily for 5 days in giardiasis
Interaction
- No reported pharmacodynamic or pharmacokinetic interactions
Contraindications
- Not normally used in neonates
- Dose reduction for children weighing less than 10 kg
- Not recommended in pregnancy or suspected pregnancy
- No evidence to alter dose in renal, hepatic, or cardiac failure
Side Effects
- Gastrointestinal disturbances
- Headache
- Dizziness
- Changes in liver enzymes
- Reversible alopecia (rare)
- Rash
- Fever
- Blood disorders
- Allergic shock if cyst leakage
- Convulsion and meningism in cerebral disease
Pregnancy & Lactation
- FDA Pregnancy category C
- Avoided in pregnancy and lactation
Precautions & Warnings
- Blood counts and liver function tests before and during treatment
- Caution in breastfeeding
- Exclusion of pregnancy before treatment
- Constant medical supervision in Echinococcosis treatment
Therapeutic Class
- Anthelmintic
Storage Conditions
- Keep in a dry place
- Away from light and heat
- Keep out of the reach of children