Amiphin 1 gm/vial (IV Injection)
1 gm vial: ৳ 200.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Ceftriaxone sodium |
| Company | Al madina pharmaceuticals ltd |
| Also available as |
Indications
- Lower respiratory tract infections
- Acute Bacterial Otitis Media
- Skin and skin structure infections
- Urinary tract infections
- Gonorrhea
- Bacterial Septicemia
- Bone and joint infections
- Meningitis
- Prevention of postoperative infections
- Perioperative prophylaxis of infections associated with surgery
Pharmacology
- Broad-spectrum parenteral cephalosporin antibiotic
- Bactericidal activity
- Gram-positive and Gram-negative organisms
- Interference with bacterial cell wall synthesis
- High stability in the presence of beta lactamases
- Relatively long plasma elimination half-life
- Non-metabolized in the body
- Excretion in the urine and bile
- Highly protein bound
Dosage
- Usual adult dose of 1 to 2 gm by intravenous or intramuscular administration
- Additional doses for specific infections
- Usual pediatric dose of 50 to 75 mg/kg intravenous or intramuscular administration
- Duration of therapy
- Variations in dosage for different types of infections
Administration
- Preparation of solutions for intramuscular/intravenous injections
- Dissolving in Lidocaine HCI or Water for injection
- Administration over 2-4 minutes
- Tubing infusion over a period of 30 minutes
- Patient tolerance test before treatment
Interaction
- No reported drug interactions
Contraindications
- Hypersensitivity to cephalosporin antibiotics
Side Effects
- Gastro-intestinal effects
- Cutaneous reactions
- Hematologic reactions
- Hepatic reactions
- CNS reactions
- Rare occurrence of local phlebitis
Pregnancy & Lactation
- Safety not established in human pregnancy
- Caution in lactating mothers
Precautions & Warnings
- Possibility of anaphylactic shock
- Sonogram findings related to gallbladder
- Blood picture checks during prolonged treatment
Use in Special Populations
- Avoidance in neonates if premature or newborn
Overdose Effects
- No specific antidote
- Symptomatic treatment
Therapeutic Class
- Third generation Cephalosporins
Storage Conditions
- Store in a cool, dry place below 30°C
- Away from light and moisture
- Keep out of reach of children