Amiphin 1 gm/vial (IV Injection)

1 gm vial: ৳ 200.00

Medicine Details

Category Details
Generic Ceftriaxone sodium
Company Al madina pharmaceuticals ltd
Also available as
Amiphin 2 gm injection

Indications

  • Lower respiratory tract infections
  • Acute Bacterial Otitis Media
  • Skin and skin structure infections
  • Urinary tract infections
  • Gonorrhea
  • Bacterial Septicemia
  • Bone and joint infections
  • Meningitis
  • Prevention of postoperative infections
  • Perioperative prophylaxis of infections associated with surgery

Pharmacology

  • Broad-spectrum parenteral cephalosporin antibiotic
  • Bactericidal activity
  • Gram-positive and Gram-negative organisms
  • Interference with bacterial cell wall synthesis
  • High stability in the presence of beta lactamases
  • Relatively long plasma elimination half-life
  • Non-metabolized in the body
  • Excretion in the urine and bile
  • Highly protein bound

Dosage

  • Usual adult dose of 1 to 2 gm by intravenous or intramuscular administration
  • Additional doses for specific infections
  • Usual pediatric dose of 50 to 75 mg/kg intravenous or intramuscular administration
  • Duration of therapy
  • Variations in dosage for different types of infections

Administration

  • Preparation of solutions for intramuscular/intravenous injections
  • Dissolving in Lidocaine HCI or Water for injection
  • Administration over 2-4 minutes
  • Tubing infusion over a period of 30 minutes
  • Patient tolerance test before treatment

Interaction

  • No reported drug interactions

Contraindications

  • Hypersensitivity to cephalosporin antibiotics

Side Effects

  • Gastro-intestinal effects
  • Cutaneous reactions
  • Hematologic reactions
  • Hepatic reactions
  • CNS reactions
  • Rare occurrence of local phlebitis

Pregnancy & Lactation

  • Safety not established in human pregnancy
  • Caution in lactating mothers

Precautions & Warnings

  • Possibility of anaphylactic shock
  • Sonogram findings related to gallbladder
  • Blood picture checks during prolonged treatment

Use in Special Populations

  • Avoidance in neonates if premature or newborn

Overdose Effects

  • No specific antidote
  • Symptomatic treatment

Therapeutic Class

  • Third generation Cephalosporins

Storage Conditions

  • Store in a cool, dry place below 30°C
  • Away from light and moisture
  • Keep out of reach of children

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