Diclomol SR 100 mg (Tablet (Sustained Release))

Unit Price: ৳ 4.00 (10 x 10: ৳ 400.00)
Strip Price: ৳ 40.00

Medicine Details

Category Details
Generic Diclofenac sodium
Company Mundipharma bd pvt ltd

Indications

  • Inflammatory and degenerative forms of rheumatism
  • Chronic involutive polyarthritis
  • Ankylosing spondylarthritis
  • Osteoarthritis
  • Acute gout
  • Sprain
  • Bruises
  • Dislocations
  • Fractures
  • Softtissue injuries
  • Episiotomy
  • Adnexitis
  • Endometritis
  • Parametritis
  • Salpingitis
  • Mastitis
  • Pre-operative medication for the prevention of pain, inflammation, and swelling
  • Post-operative and post-traumatic pain, inflammation, and swelling
  • For the prevention of pain and treatment of inflammation and swelling of patients operated in the urogenital tract
  • Renal and biliary colic

Pharmacology

  • Potent non-steroidal anti-inflammatory drug (NSAID) with pronounced anti-rheumatic, anti-inflammatory, analgesic and antipyretic properties
  • Uricosuric effect
  • Inhibits prostaglandin biosynthesis
  • Rapid and complete absorption from the gastrointestinal tract
  • Metabolized in the liver and undergoes first pass metabolism

Dosage & Administration

  • Adults: 75-150 mg daily in 2 to 3 divided doses, preferably after food
  • Children: 1-3 mg of diclofenac/kg body wt. daily in divided doses
  • Elderly patients: Lowest effective dosage recommended
  • Maximum daily dose: 150 mg

Interaction

  • May increase plasma concentrations of lithium and digoxin
  • Isolated reports of increased risk of hemorrhage with combined use of diclofenac and anticoagulant therapy
  • Can be given together with oral antidiabetic agents without influencing their clinical effect
  • Caution with concomitant therapy of NSAID and quinolones
  • Co-administration with other systemic NSAIDs and steroids may increase the frequency of unwanted effects

Contraindications

  • Hypersensitivity to any ingredient of the products
  • Peptic ulcer
  • Hypersensitivity to Diclofenac like other non-steroid anti-inflammatory agents
  • Contra-indicated in asthmatic patient in whom attack with asthma, urticaria or acute rhinitis are precipitated by acetylsalicylic acid or by other drugs with prostaglandin synthetase inhibitor
  • Should not be used under occlusive airtight dressings

Side Effects

  • Mild, rare and transient adverse effects
  • Epigastric pain
  • Eructation
  • Nausea
  • Diarrhea
  • Dizziness
  • Headache
  • Peripheral edema
  • Skin reactions such as rash and eczema
  • Local irritation and reddening of the skin
  • Skin rash

Pregnancy & Lactation

  • Employed only for compelling reasons during pregnancy
  • Lowest effective dose should be used
  • Not recommended during the first trimester of pregnancy
  • Not recommended during lactation

Precautions & Warnings

  • Close observation in rare instances of peptic ulceration or gastrointestinal bleeding
  • Keep out of contact with the eyes or mucus membranes
  • Hands should be washed properly after application
  • Not to be taken by mouth

Therapeutic Class

  • Drugs for Osteoarthritis
  • Drugs used for Rheumatoid Arthritis
  • Non-steroidal Anti-inflammatory Drugs (NSAIDs)

Storage Conditions

  • Store in a cool and dry place
  • Protected from light
  • Store below 30°C
  • Keep out of the reach of children

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