Clarimax 500 mg (Tablet)
Unit Price: ৳ 40.00 (1 x 7: ৳ 280.00)
Strip Price: ৳ 280.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Clarithromycin |
| Company | Aci limited |
| Also available as |
Indications
- Acute bacterial exacerbation of chronic bronchitis in adults
- Acute maxillary sinusitis
- Community-acquired pneumonia
- Pharyngitis or tonsillitis
- Uncomplicated skin and skin structure infections
- Acute otitis media in pediatric patients
- Treatment and prophylaxis of disseminated mycobacterial infections
- Helicobacter pylori infection and duodenal ulcer disease in adults
Pharmacology
- Inhibits microsomal protein synthesis in susceptible organisms
- Binds to the donor site on the 50S subunit of the bacterial ribosome
- Active against most Gram-positive bacteria and Chlamydia
- More acid-stable than Erythromycin
- Twice the activity of Erythromycin against H. influenzae
Dosage & Administration
- Dosage varies for different conditions and age groups
- Adult dosage for different bacterial infections
- Combination dosing regimens for H. pylori infection
- Recommended daily dosage for children
- Information on dosage adjustment for renal and hepatic impairment
Interaction
- Contraindications with specific medications
- Drug interactions with HMG-CoA reductase inhibitors, gastroprokinetic agents, ergot alkaloids, antipsychotics, anti-gout agents, and antiarrhythmics
Contraindications
- Contraindicated in patients with known hypersensitivity to clarithromycin or macrolide antibacterial drugs
- Contraindicated in patients with history of cholestatic jaundice or hepatic dysfunction associated with prior use of clarithromycin
Side Effects
- Nausea, vomiting, diarrhoea, and abdominal pain
- Stomatitis and glossitis
- Headache and allergic reactions
- Reports of transient central nervous system side effects
Pregnancy & Lactation
- Appropriate use in neonates and children
- Precautions for breastfeeding mothers receiving Clarithromycin
- Not recommended for pregnant patients
Precautions & Warnings
- Discontinuation in case of severe acute hypersensitivity reactions
- Avoidance in patients with known QT prolongation or receiving drugs known to prolong the QT interval
- Consideration of the risk of all-cause mortality in patients with coronary artery disease
- Evaluation for Clostridium difficile associated diarrhea if diarrhea occurs
Use in Special Populations
- Safety and effectiveness in pediatric patients for various conditions
- No established safety and effectiveness for MAC patients under the age of 20 months
Overdose Effects
- Gastro-intestinal symptoms with large amounts
- Reported case of altered mental status, paranoid behavior, hypokalemia, and hypoxemia with 8 grams ingestion
- Treatment of adverse reactions accompanying overdosage
Therapeutic Class
- Macrolides
Storage Conditions
- Storage in cool and dry place, protected from light & moisture
- Reconstituted suspension use within specified timeframes
- Safety precaution: Keep out of reach of children