Rosu 20 mg (Tablet)
Unit Price: ৳ 30.00 (3 x 10: ৳ 900.00)
Strip Price: ৳ 300.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Rosuvastatin calcium |
| Company | Popular pharmaceuticals ltd |
| Also available as |
Title
- Rosu 20 mg Tablet
Categories
- Medicine
- Pharmaceutical
- Healthcare
Description
- Rosu 20 mg Tablet is a HMG-CoA reductase inhibitor drug which is helpful in lowering the cholesterol level and triglycerides in the body. It is indicated for Heterozygous Hypercholesterolemia, Homozygous Hypercholesterolemia, Mixed Dyslipidemia, and primary prevention of cardiovascular disease. It is a selective and competitive inhibitor of HMG-CoA reductase, producing lipid-modifying effects by increasing the number of hepatic LDL receptors and inhibiting hepatic VLDL synthesis. The dosage range varies from 5-40 mg once daily, with specific doses for different patient populations. Rosuvastatin can be taken with or without food at any time of day. Drug interactions, contraindications, side effects, and precautions for its use are also important considerations, along with storage conditions and use in special populations like children. It belongs to the therapeutic class of Other Anti-anginal & Anti-ischaemic drugs, Statins.
Indications
- Heterozygous Hypercholesterolemia (Familial and Non familial)
- Homozygous Hypercholesterolemia (Familial)
- Mixed Dyslipidemia (Fredrickson Type IIa and IIb)
- Primary prevention of cardiovascular disease
Pharmacology
- Selective and competitive inhibitor of HMG-CoA reductase
- Converts 3-hydroxy-3-methyl glutaryl coenzyme A to mevalonate, a precursor of cholesterol
- Increases hepatic LDL receptors on the cell surface
- Inhibits hepatic synthesis of VLDL
Dosage
- Dose range: 5-40 mg once daily
- Starting dose 20 mg/day for HoFH
- Pediatric patients with HeFH: 5-10 mg/day for 8 to less than 10 years age
- Pediatric patients with HoFH: 20 mg/day for 7 to 17 years of age
Administration
- Can be taken with or without food, at any time of day
Interaction
- Cyclosporine increases Rosu exposure. Dose should be limited to 5 mg once daily
- Gemfibrosil combination should be avoided. If used together, dose should be limited to 10 mg once daily
- Concomitant lipid-lowering therapies may increase the risk of skeletal muscle effects
Contraindications
- Known hypersensitivity to product components
- Liver disease, including unexplained persistent elevations in hepatic transaminase levels
- Pregnant women and women who may become pregnant
- Nursing mothers
Side effects
- Headache
- Myalgia
- Constipation
- Asthenia
- Abdominal pain
- Nausea
Pregnancy lactation
- Safety in pregnant women not established
- Not known whether excreted in human milk
Precautions warnings
- Risks increase with use of 40 mg dose, advanced age, hypothyroidism, renal impairment, and combination use with certain other drugs
- Liver enzyme abnormalities and monitoring required
- Safety and effectiveness in pediatric patients not established
Special populations
- Use in children: Safety and effectiveness not established
Therapeutic class
- Other Anti-anginal & Anti-ischaemic drugs
- Statins
Storage conditions
- Keep below 30°C temperature
- Protected from light & moisture
- Keep out of the reach of children
Chemical structure
- Molecular Formula: C22H28FN3O6S
- Chemical Structure available as an image
Common questions
- What is Rosu 20 mg Tablet?
- What are the uses of Rosu 20 mg Tablet?
- What are the side effects of Rosu 20 mg Tablet?
- For how long should I take Rosu 20 mg Tablet?
- Does Rosu 20 mg Tablet cause weight gain?
- Does Rosu 20 mg Tablet make you tired?
- Should Rosu 20 mg Tablet be taken at night?
- What foods should be avoided when taking Rosu 20 mg Tablet?
- How do I know whether Rosu 20 mg Tablet is beneficial for me or not?
- Can Rosu 20 mg Tablet cause memory loss?
- Is it true that Rosu 20 mg Tablet can cause diabetes?
- Can I take alcohol with Rosu 20 mg Tablet?
- Can Rosu 20 mg Tablet cause muscle problems or muscle injury?
- Quick Tips
Features
- Lowers cholesterol level and triglycerides
- Selective and competitive HMG-CoA reductase inhibitor
- Increases hepatic LDL receptors and inhibits VLDL synthesis
- Available in doses ranging from 5-40 mg
- Can be taken with or without food
- Has specific interactions and contraindications
- Approved for primary prevention of cardiovascular disease
- Requires monitoring in special populations like children
- Belongs to the therapeutic class of Statins