Soritin 25 mg (Capsule)
Unit Price: ৳ 85.00 (1 x 10: ৳ 850.00)
Strip Price: ৳ 850.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Acitretin |
| Company | Opsonin pharma ltd |
| Also available as |
Indications
- Severe extensive psoriasis
- Palmo-plantar pustular psoriasis
- Severe congenital ichthyosis
- Severe Darier's disease
Pharmacology
- Aromatic analogue of vitamin A
- Regulation of RNA/DNA synthesis
- Modulation of epidermal proliferation
- Modification of glycoprotein synthesis
- Modulation of immune response
Dosage & Administration
- Initial daily dose for adults and elderly: 25-30 mg
- Daily dosage for adults and elderly: 25-50 mg
- Starting dose for Darier's disease: 10 mg
- Daily dosage for children: 0.5 mg/kg
- Maximum dosage for children: 35 mg/day
Interaction
- Concurrent intake with ethanol forms etretinate
- Contraindicated with methotrexate, tetracyclines, vitamin A, other retinoids, and phenytoin
Contraindications
- Highly teratogenic
- Contraindicated in pregnant women
- Contraindicated in women of childbearing potential without strict contraception
- Contraindicated in patients with severe hepatic or renal impairment
Side Effects
- Most patients experience dose-related side-effects
- Adverse effects primarily affect skin and mucous membranes
- Initial worsening of psoriasis symptoms may occur
Pregnancy & Lactation
- Contraindicated in pregnant women
- Contraindicated in nursing mothers
Precautions & Warnings
- Exceptionally high risk of giving birth to a deformed child if taken before or during pregnancy
- Enhanced effects of UV light
- Regular monitoring of hepatic function, serum cholesterol, and serum triglycerides
Overdose Effects
- Manifestations of acute vitamin A toxicity
- Specific treatment unnecessary due to low acute toxicity
Therapeutic Class
- Oral Retinoid preparations
Storage Conditions
- Store in cool & dry place
- Protected from light
- Do not store above 25°C